The substantial investments in human genetics and genomics made over the past three
decades were anticipated to result in many innovative therapies. Here we investigate the …

Genetic studies are under way for many complex traits, spurred by the recent feasibility of
whole genome scans. Clear guidelines for the interpretation of linkage results are needed to …

Identifying causal factors for Mendelian and common diseases is an ongoing challenge in
medical genetics. Population bottleneck events, such as those that occurred in the history of …

Psychological researchers typically distinguish five major domains of individual differences
in human behavior: cognitive abilities, personality, social attitudes, psychological interests …

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …

The historical and genetic foundations of our current understanding of schizophrenia are
reviewed, as are the present and future directions for research. Genetic epidemiological …

Badner and Gershon (2001) presented a technique of meta-analysis of linkage data that
could be applied to published genome scans. It combines the reported P-values of …

Schizophrenia is a psychiatric disorder that a icts 0.5±1% of the general population. It is
clinically characterized by disturbed thought processes, delusions, hallucinations and/or …

Attention deficit hyperactivity disorder (ADHD) is a complex condition with environmental
and genetic etiologies. Up to this point, research has identified genetic associations with …

Eaton WW, Pedersen MG, Nielsen PR, Mortensen PB. Autoimmune diseases, bipolar
disorder, and non‐affective psychosis. Bipolar Disord 2010: 12: 638–646.© 2010 The …