Deadly proteomes: a practical guide to proteotranscriptomics of animal venoms

AA Walker, SD Robinson, BF Hamilton… - …, 2020 - Wiley Online Library
Animal venoms are renowned for their toxicity, biochemical complexity, and as a source of
compounds with potential applications in medicine, agriculture, and industry. Polypeptides …

Scorpion venom–toxins that aid in drug development: a review

A Ghosh, R Roy, M Nandi, A Mukhopadhyay - International journal of …, 2019 - Springer
Scorpion venom components have multifaceted orientation against bacterial, viral, fungal
infections and other neuronal disorders. They can modulate the ion channels (K+, Na+, Cl …

Venom proteomic and venomous glands transcriptomic analysis of the Egyptian scorpion Scorpio maurus palmatus (Arachnida: Scorpionidae)

MA Abdel-Rahman, V Quintero-Hernandez… - Toxicon, 2013 - Elsevier
Proteomic analysis of the scorpion venom Scorpio maurus palmatus was performed using
reverse-phase HPLC separation followed by mass spectrometry determination. Sixty five …

Evolution stings: the origin and diversification of scorpion toxin peptide scaffolds

K Sunagar, EAB Undheim, AHC Chan, I Koludarov… - Toxins, 2013 - mdpi.com
The episodic nature of natural selection and the accumulation of extreme sequence
divergence in venom-encoding genes over long periods of evolutionary time can obscure …

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion

K Luna-Ramírez, V Quintero-Hernandez… - PloS one, 2015 - journals.plos.org
Australian scorpion venoms have been poorly studied, probably because they do not pose
an evident threat to humans. In addition, the continent has other medically important …

Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus

V Quintero-Hernández, S Ramírez-Carreto… - PloS one, 2015 - journals.plos.org
Scorpions belonging to the Buthidae family have traditionally drawn much of the
biochemist's attention due to the strong toxicity of their venoms. Scorpions not toxic to …

Snapshots of scorpion venomics

MA Abdel-Rahman, PL Harrison, PN Strong - Journal of Arid Environments, 2015 - Elsevier
Scorpions are particularly well adapted to survival in extreme habitats (especially arid and
semi-arid environments) and their ability to produce and deliver venoms is an important …

Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus

T Olamendi-Portugal, A Bartok, F Zamudio-Zuñiga… - Toxicon, 2016 - Elsevier
Six new peptides were isolated from the venom of the Mexican scorpion Centruroides
tecomanus; their primary structures were determined and the effects on ion channels were …

[PDF][PDF] Insect venoms and their bioactive components: A novel therapeutic approach in chronic diseases and cancer

D Moran, U Dutta, AB Kunnumakkara… - Journal of Cancer …, 2022 - fortunepublish.com
To counteract the growing burden of chronic diseases, discovery of highly selective target
specific drugs is of utmost importance in present scenario. Various advanced therapeutic …

Investigating the inhibitory and penetrating properties of three novel anticancer and antimicrobial scorpion peptides via molecular docking and molecular dynamic …

E Jahangirian, J Zargan, H Rabbani… - Journal of Biomolecular …, 2023 - Taylor & Francis
The two types of bladder cancer, muscle invasive and non-muscle invasive (NMIBC), are
among the most prevalent cancers worldwide. Despite this, even though muscle-invasive …