A review of the current state of magnetic force microscopy to unravel the magnetic properties of nanomaterials applied in biological systems and future directions for …
Magnetism plays a pivotal role in many biological systems. However, the intensity of the
magnetic forces exerted between magnetic bodies is usually low, which demands the …
magnetic forces exerted between magnetic bodies is usually low, which demands the …
Recent advances in amorphous solid dispersions: preformulation, formulation strategies, technological advancements and characterization
Amorphous solid dispersions (ASDs) are among the most popular and widely studied
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
Amorphous solid dispersions: Utilization and challenges in preclinical drug development within AstraZeneca
AB Anane-Adjei, E Jacobs, SC Nash, S Askin… - International Journal of …, 2022 - Elsevier
The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …
much of the early drug development portfolio and poses a major challenge in …
Role of surfactants in improving release from higher drug loading amorphous solid dispersions
Amorphous solid dispersion formulations (ASD) are increasingly being used as a
formulation strategy to improve bioavailability of poorly soluble drugs. One of the limitations …
formulation strategy to improve bioavailability of poorly soluble drugs. One of the limitations …
Interplay of drug–polymer interactions and release performance for hpmcas-based amorphous solid dispersions
The interplay between drug and polymer chemistry and its impact on drug release from an
amorphous solid dispersion (ASD) is a relatively underexplored area. Herein, the release …
amorphous solid dispersion (ASD) is a relatively underexplored area. Herein, the release …
Crystallinity: a complex critical quality attribute of amorphous solid dispersions
DE Moseson, LS Taylor - Molecular Pharmaceutics, 2023 - ACS Publications
Does the performance of an amorphous solid dispersion rely on having 100% amorphous
content? What specifications are appropriate for crystalline content within an amorphous …
content? What specifications are appropriate for crystalline content within an amorphous …
Supersaturation and phase behavior during dissolution of amorphous solid dispersions
Y Kong, W Wang, C Wang, L Li, D Peng… - International Journal of …, 2023 - Elsevier
Amorphous solid dispersion (ASD) is a promising strategy to enhance solubility and
bioavailability of poorly water-soluble drugs. Due to higher free energy of ASD …
bioavailability of poorly water-soluble drugs. Due to higher free energy of ASD …
Effects of additives on the physical stability and dissolution of polymeric amorphous solid dispersions: A review
Polymeric amorphous solid dispersion (ASD) is a popular approach for enhancing the
solubility of poorly water-soluble drugs. However, achieving both physical stability and …
solubility of poorly water-soluble drugs. However, achieving both physical stability and …
Phase separation in surfactant-containing amorphous solid dispersions: Orthogonal analytical methods to probe the effects of surfactants on morphology and phase …
Amorphous–amorphous phase separation (AAPS) is an important phase transition process
for amorphous solid dispersion (ASD) performance both in terms of drug release as well as …
for amorphous solid dispersion (ASD) performance both in terms of drug release as well as …
[HTML][HTML] In-situ formation of nanoparticles from drug-loaded 3D polymeric matrices
The in-situ formation of nanoparticles from polymer-based solid medicines, although
previously described, has been overlooked despite its potential to interfere with oral drug …
previously described, has been overlooked despite its potential to interfere with oral drug …