Adaptation in auditory processing

BDB Willmore, AJ King - Physiological Reviews, 2023 - journals.physiology.org
Adaptation is an essential feature of auditory neurons, which reduces their responses to
unchanging and recurring sounds and allows their response properties to be matched to the …

Functional network properties of the auditory cortex

JH Lestang, H Cai, BB Averbeck, YE Cohen - Hearing research, 2023 - Elsevier
The auditory system transforms auditory stimuli from the external environment into
perceptual auditory objects. Recent studies have focused on the contribution of the auditory …

Oncomodulin regulates spontaneous calcium signalling and maturation of afferent innervation in cochlear outer hair cells

Y Yang, K Murtha, LK Climer, F Ceriani… - The Journal of …, 2023 - Wiley Online Library
Cochlear outer hair cells (OHCs) are responsible for the exquisite frequency selectivity and
sensitivity of mammalian hearing. During development, the maturation of OHC afferent …

Decreased modulation of population correlations in auditory cortex is associated with decreased auditory detection performance in old mice

K Shilling-Scrivo, J Mittelstadt… - Journal of …, 2022 - Soc Neuroscience
Age-related hearing loss (presbycusis) affects one-third of the world's population. One
hallmark of presbycusis is difficulty hearing in noisy environments. Presbycusis can be …

Transient brain-wide coactivations and structured transitions revealed in hemodynamic imaging data

AF Khan, F Zhang, G Shou, H Yuan, L Ding - Neuroimage, 2022 - Elsevier
Brain-wide patterns in resting human brains, as either structured functional connectivity (FC)
or recurring brain states, have been widely studied in the neuroimaging literature. In …

Perinatal opioid exposure results in persistent hypoconnectivity of excitatory circuits and reduced activity correlations in mouse primary auditory cortex

B Xue, JB Alipio, JPY Kao, PO Kanold - Journal of Neuroscience, 2022 - Soc Neuroscience
Opioid use by pregnant women results in neonatal opioid withdrawal syndrome (NOWS)
and lifelong neurobehavioral deficits including language impairments. Animal models of …

Long-term training alters response dynamics in the aging auditory cortex

JK Mittelstadt, KV Shilling-Scrivo, PO Kanold - Hearing Research, 2024 - Elsevier
Age-related auditory dysfunction, presbycusis, is caused in part by functional changes in the
auditory cortex (ACtx) such as altered response dynamics and increased population …

Age-related changes in excitatory and inhibitory intra-cortical circuits in auditory cortex of C57Bl/6 mice

B Xue, X Meng, JPY Kao, PO Kanold - Hearing research, 2023 - Elsevier
A common impairment in aging is age-related hearing loss (presbycusis), which manifests
as impaired spectrotemporal processing. Aging is accompanied by alteration in normal …

Interactive auditory task reveals complex sensory-action integration in mouse primary auditory cortex

J Liu, PO Kanold - bioRxiv, 2022 - biorxiv.org
Predictive coding theory postulates that the brain achieves perception by actively making
predictions about the incoming sensory information and correcting them if errors signals …

Automated head-fixation training system with high levels of animal participation in psychoacoustic tasks

J Liu, K Maximov, PO Kanold - bioRxiv, 2022 - biorxiv.org
Many animal training paradigms rely on head-fixation. Head-fixation training is typically
laborious and can benefit from automation to relieve the workload as well as to reduce the …