Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …
continues to afflict hundreds of millions of people every year. Infections with malaria …
[HTML][HTML] Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
Lineage-informative microhaplotypes for recurrence classification and spatio-temporal surveillance of Plasmodium vivax malaria parasites
Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of
antimalarial efficacy and transmission. Recurrent infections may arise from activation of …
antimalarial efficacy and transmission. Recurrent infections may arise from activation of …
Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …
Systems biology of malaria explored with nonhuman primates
MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross
Mainstay treatment for Plasmodium vivax malaria has long relied on chloroquine (CQ)
against blood-stage parasites plus primaquine against dormant liver-stage forms …
against blood-stage parasites plus primaquine against dormant liver-stage forms …
Recrudescence, Reinfection, or Relapse? A More Rigorous Framework to Assess Chloroquine Efficacy for Plasmodium vivax Malaria
J Popovici, L Pierce-Friedrich, S Kim… - The Journal of …, 2019 - academic.oup.com
Background Plasmodium vivax resistance to chloroquine (CQ) has been reported
worldwide, although the World Health Organization clinical drug efficacy studies protocol …
worldwide, although the World Health Organization clinical drug efficacy studies protocol …
Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts
B Hazzard, JM Sá, AC Ellis, TV Pascini… - PLOS Neglected …, 2022 - journals.plos.org
Plasmodium vivax infections often consist of heterogenous populations of parasites at
different developmental stages and with distinct transcriptional profiles, which complicates …
different developmental stages and with distinct transcriptional profiles, which complicates …
Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion
C Roesch, J Popovici, S Bin, V Run, S Kim… - PLoS neglected …, 2018 - journals.plos.org
The interaction between Plasmodium vivax Duffy binding protein (PvDBP) and Duffy antigen
receptor for chemokines (DARC) has been described as critical for the invasion of human …
receptor for chemokines (DARC) has been described as critical for the invasion of human …
Population genomics identifies a distinct Plasmodium vivax population on the China-Myanmar border of Southeast Asia
AM Brashear, Q Fan, Y Hu, Y Li, Y Zhao… - PLoS Neglected …, 2020 - journals.plos.org
Plasmodium vivax has become the predominant malaria parasite and a major challenge for
malaria elimination in the Greater Mekong Subregion (GMS). Yet, our knowledge about the …
malaria elimination in the Greater Mekong Subregion (GMS). Yet, our knowledge about the …