Biological variation (BV) data have many important applications in laboratory medicine.
Concerns about quality of published BV data led the European Federation of Clinical …

Biological variation (BV) data have many applications in laboratory medicine. However,
these depend on the availability of relevant and robust BV data fit for purpose. BV data can …

Using laboratory test results for diagnosis and monitoring requires a reliable reference to
which the results can be compared. Currently, most reference data is derived from the …

Background For biological variation (BV) data to be safely used, data must be reliable and
relevant to the population in which they are applied. We used samples from the European …

Background Biological variation (BV) data may be used to develop analytical performance
specifications (APS), reference change values (RCV), and support the applicability of …

Biological variation (BV) is one of the most important sources contributing to uncertainty in
laboratory examinations and should be taken into account in any interpretation made. There …

Copeptin is used as a sensitive surrogate marker of ADH (antidiuretic hormone) when
investigating fluid imbalance such as in diabetes insipidus, SIADH (syndrome of …

Objectives The estimates of biological variation (BV) have traditionally been determined
using direct methods, which present limitations. In response to this issue, two papers have …

Background The European Biological Variation Study (EuBIVAS) was created by the
European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group …

Objectives Within-and between-subject biological variation (BV) estimates have many
applications in laboratory medicine. However, robust high-quality BV estimates are lacking …