Transthyretin amyloid cardiomyopathy (ATTR-CM) is an under-recognized cause of heart
failure (HF) in older adults, resulting from myocardial deposition of misfolded transthyretin …

Sharmila Dorbala, MD, MPH, FASNC, Chair*; Yukio Ando, MD, PhD†; Sabahat Bokhari,
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …

Background—Cardiac transthyretin (ATTR) amyloidosis is a progressive and fatal
cardiomyopathy for which several promising therapies are in development. The diagnosis is …

The amyloidoses are a group of protein-folding disorders in which≥ 1 organ is infiltrated by
proteinaceous deposits known as amyloid. The deposits are derived from 1 of several …

Abstract Cardiovascular Magnetic Resonance is increasingly used to differentiate the
aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference …

Advances in cardiac imaging have resulted in greater recognition of cardiac amyloidosis in
everyday clinical practice, but the diagnosis continues to be made in patients with late-stage …

Background: Cardiac transthyretin amyloidosis (ATTR) is an increasingly recognized cause
of heart failure. Cardiac magnetic resonance (CMR), with late gadolinium enhancement …

Background—The prognosis and treatment of the 2 main types of cardiac amyloidosis,
immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are substantially …

Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive
neuropathy and cardiomyopathy. It occurs in both a mutant form (with autosomal dominant …

Importance Transthyretin cardiac amyloidosis (also known as ATTR cardiac amyloidosis) is
an increasingly recognized cause of heart failure with preserved ejection fraction. In single …