The circadian clock is a complex cellular mechanism that, through the control of diverse
metabolic and gene expression pathways, governs a large array of cyclic physiological …

Most organisms display endogenously produced∼ 24-hour fluctuations in physiology and
behavior, termed circadian rhythms. Circadian rhythms are driven by a transcriptional …

Plastic pollution is a growing global emergency and it could serve as a geological indicator
of the Anthropocene era. Microplastics are potentially more hazardous than macroplastics …

The process of aging and circadian rhythms are intimately intertwined, but how peripheral
clocks involved in metabolic homeostasis contribute to aging remains unknown. Importantly …

Circadian rhythms have natural relative variations among humans known as chronotype.
Chronotype or being a morning or evening person, has a specific physiological …

Mammalian circadian rhythms are controlled by endogenous biological oscillators, including
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …

Brain aging is associated with diminished circadian clock output and decreased expression
of the core clock proteins, which regulate many aspects of cellular biochemistry and …

The global increase in the prevalence of obesity and metabolic disorders coincides with the
increase of exposure to light at night (LAN) and shift work. Circadian regulation of energy …

Time in the biological sense is measured by cycles that range from milliseconds to years.
Circadian rhythms, which measure time on a scale of 24 h, are generated by one of the most …

The incidence of obesity and type 2 diabetes mellitus (T2DM) has risen to epidemic
proportions. The pathophysiology of T2DM is complex and involves insulin resistance …