A scoping review of the functional magnetic resonance imaging‐based functional connectivity of focal cortical dysplasia‐related epilepsy

NT Cohen, H Xie, T Gholipour, WD Gaillard - Epilepsia, 2023 - Wiley Online Library
Focal cortical dysplasia (FCD) is the most frequent etiology of operable pharmacoresistant
epilepsy in children. There is burgeoning evidence that FCD‐related epilepsy is a disorder …

The clinical, imaging, pathological and genetic landscape of bottom-of-sulcus dysplasia

E Macdonald-Laurs, AEL Warren, P Francis… - Brain, 2024 - academic.oup.com
Bottom-of-sulcus dysplasia (BOSD) is increasingly recognized as a cause of drug-resistant,
surgically-remediable, focal epilepsy, often in seemingly MRI-negative patients. We describe …

WONOEP 2022: Neurotechnology for the diagnosis of epilepsy

K Wagstyl, K Kobow, PM Casillas‐Espinosa… - …, 2024 - Wiley Online Library
Epilepsy's myriad causes and clinical presentations ensure that accurate diagnoses and
targeted treatments remain a challenge. Advanced neurotechnologies are needed to better …

Multimodal mapping of regional brain vulnerability to focal cortical dysplasia

HM Lee, SJ Hong, R Gill, B Caldairou, I Wang, J Zhang… - Brain, 2023 - academic.oup.com
Focal cortical dysplasia (FCD) type II is a highly epileptogenic developmental malformation
and a common cause of surgically treated drug-resistant epilepsy. While clinical …

Mapping Functional Connectivity Signatures of Pharmacoresistant Focal Cortical Dysplasia‐Related Epilepsy

H Xie, VSP Illapani, LG Vezina, T Gholipour… - Annals of …, 2024 - Wiley Online Library
Objective To determine common network alterations in focal cortical dysplasia
pharmacoresistant epilepsy (FCD‐PRE) using functional connectivity analysis of resting …

Why did my seizures start now? Influences of lesion connectivity and genetic etiology on age at seizure onset in focal epilepsy

E Macdonald‐Laurs, AEL Warren, RJ Leventer… - …, 2024 - Wiley Online Library
Objective Patients with focal, lesional epilepsy present with seizures at variable ages. Larger
lesion size and overlap with sensorimotor or default mode network (DMN) have been …

Application of preoperative MRI lesion identification algorithm in pediatric and young adult focal cortical dysplasia-related epilepsy

KL Hom, VSP Illapani, H Xie, C Oluigbo… - … : European Journal of …, 2024 - Elsevier
Objective The purpose of this study was to evaluate the performance and generalizability of
an automated, interpretable surface-based MRI classifier for the detection of focal cortical …

To explore the potential mechanisms of cognitive impairment in children with MRI-negative pharmacoresistant epilepsy due to focal cortical dysplasia: A pilot study …

Y Zhao, J Lin, X Qi, D Cao, F Zhu, L Chen, Z Tan, T Mo… - Heliyon, 2024 - cell.com
Objectives To investigate the characteristics of brain structure in children with focal cortical
dysplasia (FCD)-induced pharmacoresistant epilepsy, and explore the potential …

seizure-related consolidation and the network theory of epilepsy

MR Bower - Frontiers in Network Physiology, 2024 - frontiersin.org
Epilepsy is a complex, multifaceted disease that affects patients in several ways in addition
to seizures, including psychological, social, and quality of life issues, but epilepsy is also …

Limbic network co‐localization predicts pharmacoresistance in dysplasia‐related epilepsy

NT Cohen, P Chang, T Gholipour… - Annals of Clinical …, 2023 - Wiley Online Library
To evaluate the role of focal cortical dysplasia co‐localization to cortical functional networks
in the development of pharmacoresistance. One hundred thirty‐six focal cortical dysplasia …