Understanding how activity patterns in specific neural circuits coordinate an animal's
behavior remains a key area of neuroscience research. Genetic tools and a brain of …

The diversity of cell types and regulatory states in the brain, and how these change during
aging, remains largely unknown. We present a single-cell transcriptome atlas of the entire …

Sleep is a biological enigma that has raised numerous questions about the inner workings
of the brain. The fundamental question of why our nervous systems have evolved to require …

Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

Assigning behavioral functions to neural structures has long been a central goal in
neuroscience and is a necessary first step toward a circuit-level understanding of how the …

Small, genetically tractable species such as larval zebrafish, Drosophila, or Caenorhabditis
elegans have become key model organisms in modern neuroscience. In addition to their low …

Animals perform many stereotyped movements, but how nervous systems are organized for
controlling specific movements remains unclear. Here we use anatomical, optogenetic …

Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

Highlights•Drosophila larva enables combining comprehensive synapse resolution
connectivity maps with cellular-resolution activity maps and behavior maps.•This approach …

Rhythmic movements are ubiquitous in animal locomotion, feeding and circulatory systems.
In some systems, the muscle itself generates rhythmic contractions. In others, rhythms are …