Hypoxemia, oxygen content, and the regulation of cerebral blood flow

RL Hoiland, AR Bain, MG Rieger… - American Journal …, 2016 - journals.physiology.org
This review highlights the influence of oxygen (O2) availability on cerebral blood flow (CBF).
Evidence for reductions in O2 content (CaO2) rather than arterial O2 tension (PaO2) as the …

Blood flow in the cerebral capillary network: a review emphasizing observations with intravital microscopy

AG Hudetz - Microcirculation, 1997 - Taylor & Francis
Capillary perfusion in the brain is characterized by an essentially continuous flow of
erythrocytes and plasma in almost all capillaries. Rapid fluctuations and spatial …

Relation of blood viscosity to demographic and physiologic variables and to cardiovascular risk factors in apparently normal adults.

G De Simone, RB Devereux, S Chien, MH Alderman… - Circulation, 1990 - Am Heart Assoc
Although increased blood viscosity occurs in several cardiovascular diseases, little is known
of factors influencing blood rheology in normal adults. Accordingly, we examined the …

Traumatic cerebral vascular injury: the effects of concussive brain injury on the cerebral vasculature

DS DeWitt, DS Prough - Journal of neurotrauma, 2003 - liebertpub.com
In terms of human suffering, medical expenses, and lost productivity, head injury is one of
the major health care problems in the United States, and inadequate cerebral blood flow is …

Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage

J Sen, A Belli, H Albon, L Morgan, A Petzold… - The Lancet …, 2003 - thelancet.com
Cerebral vasospasm is a recognised but poorly understood complication for many patients
who have aneurismal subarachnoid haemorrhage and can lead to delayed ischaemic …

Transcranial Doppler measurements of the middle cerebral artery. Effect of hematocrit.

LM Brass, SG Pavlakis, D DeVivo, S Piomelli, JP Mohr - Stroke, 1988 - Am Heart Assoc
We evaluated the effects of hematocrit on blood velocity in the middle cerebral artery
measured by transcranial Doppler ultrasonography in 45 patients. Hematocrits ranged from …

Increased brain capillaries in chronic hypoxia

JA Boero, J Ascher, A Arregui… - Journal of applied …, 1999 - journals.physiology.org
The effect of chronic hypobaric hypoxia (28 days, 455 Torr) on the organization of brain
vessels was studied in Balb/c mice. In comparison to age-matched controls kept at sea level …

The triphasic effects of exercise on blood rheology: which relevance to physiology and pathophysiology?

JF Brun, S Khaled, E Raynaud, D Bouix… - Clinical …, 1998 - content.iospress.com
The life‐extending effects of regular exercise are related to a decrease in both coronary and
peripheral vascular morbidity, associated with some improvements in cardiovascular risk …

Intracranial hypertension in Africans with cerebral malaria

C Newton, J Crawley, A Sowumni, C Waruiru… - Archives of Disease in …, 1997 - adc.bmj.com
The causes of death and neurological sequelae in African children with cerebral malaria are
obscure. Intracranial pressure (ICP) was monitored and cerebral perfusion pressure (CPP) …

Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans

RB Weiskopf, J Feiner, H Hopf, J Lieberman… - The Journal of the …, 2006 - pubs.asahq.org
Background Erythrocytes are transfused to treat or prevent imminent inadequate tissue
oxygenation. 2, 3-diphosphoglycerate concentration decreases and oxygen affinity of …