The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection
P Wang, R Luo, M Zhang, Y Wang, T Song, T Tao… - Cell death & …, 2020 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is an acute and rapidly developing pandemic,
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages
E Pellegrino, B Aylan, C Bussi, A Fearns… - Journal of Cell …, 2023 - rupress.org
Peroxisomes are organelles involved in many metabolic processes including lipid
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …
Peroxisomes as cellular adaptors to metabolic and environmental stress
Peroxisomes are involved in multiple metabolic processes, including fatty acid oxidation,
ether lipid synthesis, and reactive oxygen species (ROS) metabolism. Recent studies …
ether lipid synthesis, and reactive oxygen species (ROS) metabolism. Recent studies …
Peroxisomes in immune response and inflammation
The immune response is essential to protect organisms from infection and an altered self. An
organism's overall metabolic status is now recognized as an important and long-overlooked …
organism's overall metabolic status is now recognized as an important and long-overlooked …
COVID‐19 induces neuroinflammation and suppresses peroxisomes in the brain
A Roczkowsky, D Limonta, JP Fernandes… - Annals of …, 2023 - Wiley Online Library
Objective Peroxisome injury occurs in the central nervous system (CNS) during multiple
virus infections that result in neurological disabilities. We investigated host neuroimmune …
virus infections that result in neurological disabilities. We investigated host neuroimmune …
Restructured membrane contacts rewire organelles for human cytomegalovirus infection
KC Cook, E Tsopurashvili, JM Needham… - Nature …, 2022 - nature.com
Membrane contact sites (MCSs) link organelles to coordinate cellular functions across space
and time. Although viruses remodel organelles for their replication cycles, MCSs remain …
and time. Although viruses remodel organelles for their replication cycles, MCSs remain …
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection
Y Hashimoto, X Sheng, LA Murray-Nerger… - Nature …, 2020 - nature.com
The co-evolution and co-existence of viral pathogens with their hosts for millions of years is
reflected in dynamic virus-host protein-protein interactions (PPIs) that are intrinsic to the …
reflected in dynamic virus-host protein-protein interactions (PPIs) that are intrinsic to the …
Virus impact on lipids and membranes
E Ketter, G Randall - Annual review of virology, 2019 - annualreviews.org
Viruses manipulate cellular lipids and membranes at each stage of their life cycle. This
includes lipid-receptor interactions, the fusion of viral envelopes with cellular membranes …
includes lipid-receptor interactions, the fusion of viral envelopes with cellular membranes …