Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
Concise review: MSC-derived exosomes for cell-free therapy
DG Phinney, MF Pittenger - Stem cells, 2017 - academic.oup.com
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
Extracellular vesicles as personalized medicine
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …
intercellular communication network that contributes to health and disease. The contents of …
Exosome-mediated delivery of hydrophobically modified siRNA for huntingtin mRNA silencing
Delivery represents a significant barrier to the clinical advancement of oligonucleotide
therapeutics for the treatment of neurological disorders, such as Huntington's disease …
therapeutics for the treatment of neurological disorders, such as Huntington's disease …
Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer
H Nie, X Xie, D Zhang, Y Zhou, B Li, F Li, F Li, Y Cheng… - Nanoscale, 2020 - pubs.rsc.org
Engineered exosomes have become popular drug delivery carriers for cancer treatment.
This is partially due to the interesting property, ie exosome organotropism, which plays an …
This is partially due to the interesting property, ie exosome organotropism, which plays an …
Role of exosomes in central nervous system diseases
W Liu, X Bai, A Zhang, J Huang, S Xu… - Frontiers in molecular …, 2019 - frontiersin.org
There are many types of intercellular communication, and extracellular vesicles are one of
the important forms of this. They are released by a variety of cell types, are heterogeneous …
the important forms of this. They are released by a variety of cell types, are heterogeneous …
The emerging antioxidant paradigm of mesenchymal stem cell therapy
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …
the treatment of diverse diseases, with many promising outcomes achieved in animal …
Recent advances in biomimetic nanodelivery systems: new brain-targeting strategies
J Liao, L Fan, Y Li, QQ Xu, LY Xiong, SS Zhang… - Journal of Controlled …, 2023 - Elsevier
In recent years, brain diseases have seriously threatened human health due to their high
morbidity and mortality. Achieving efficient drug delivery to provide satisfactory therapeutic …
morbidity and mortality. Achieving efficient drug delivery to provide satisfactory therapeutic …
Stem cell-derived exosomes: a new strategy of neurodegenerative disease treatment
N Fayazi, M Sheykhhasan, S Soleimani Asl… - Molecular …, 2021 - Springer
Short-term symptomatic treatment and dose-dependent side effects of pharmacological
treatment for neurodegenerative diseases have forced the medical community to seek an …
treatment for neurodegenerative diseases have forced the medical community to seek an …
Extracellular vesicles, from the pathogenesis to the therapy of neurodegenerative diseases
X Xia, Y Wang, JC Zheng - Translational Neurodegeneration, 2022 - Springer
Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …