Progress in stem cell therapy for spinal cord injury

L Gao, Y Peng, W Xu, P He, T Li, X Lu… - Stem Cells …, 2020 - Wiley Online Library
Background. Spinal cord injury (SCI) is one of the serious neurological diseases that occur
in young people with high morbidity and disability. However, there is still a lack of effective …

Current options for cell therapy in spinal cord injury

I Vismara, S Papa, F Rossi, G Forloni… - Trends in molecular …, 2017 - cell.com
Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical
injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes …

[HTML][HTML] Multimodal treatment for spinal cord injury: a sword of neuroregeneration upon neuromodulation

Y Zheng, YR Mao, TF Yuan, DS Xu… - Neural regeneration …, 2020 - journals.lww.com
Spinal cord injury is linked to the interruption of neural pathways, which results in
irreversible neural dysfunction. Neural repair and neuroregeneration are critical goals and …

[HTML][HTML] Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury

S Gao, X Guo, S Zhao, Y Jin, F Zhou, P Yuan… - Cell death & …, 2019 - nature.com
Human adipose-derived stem cells (hADSCs) are increasingly presumed to be a
prospective stem cell source for cell replacement therapy in various degenerative and/or …

Stem cell paracrine effect and delivery strategies for spinal cord injury regeneration

V Veneruso, F Rossi, A Villella, A Bena… - Journal of Controlled …, 2019 - Elsevier
Spinal cord injury (SCI) is a complicated neuropathological condition that results in
functional dysfunction and paralysis. Various treatments have been proposed including …

The efficacy and safety of mesenchymal stem cell transplantation for spinal cord injury patients: a meta-analysis and systematic review

P Xu, X Yang - Cell transplantation, 2019 - journals.sagepub.com
Spinal cord injury (SCI) is a devastating disease, with a high rate of disability. In this meta-
analysis, we aimed to comprehensively assess the efficacy and safety of mesenchymal stem …

Promoting 3D neuronal differentiation in hydrogel for spinal cord regeneration

P Zhou, P Xu, J Guan, C Zhang, J Chang… - Colloids and Surfaces B …, 2020 - Elsevier
Spinal cord injury (SCI) affects millions of people worldwide, and results in the loss of
neurons and limited recovery of functions. Bone mesenchymal stem cells (BMSCs) and …

Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

[HTML][HTML] Harnessing the neural stem cell secretome for regenerative neuroimmunology

CM Willis, AM Nicaise, R Hamel, V Pappa… - Frontiers in cellular …, 2020 - frontiersin.org
Increasing evidence foresees the secretome of neural stem cells (NSCs) to confer
superimposable beneficial properties as exogenous NSC transplants in experimental …

[HTML][HTML] Human-induced neural and mesenchymal stem cell therapy combined with a curcumin nanoconjugate as a spinal cord injury treatment

P Bonilla, J Hernandez, E Giraldo… - International journal of …, 2021 - mdpi.com
We currently lack effective treatments for the devastating loss of neural function associated
with spinal cord injury (SCI). In this study, we evaluated a combination therapy comprising …