Membrane proteins are embedded in lipid bilayers and facilitate the communication
between the external environment and the interior of the cell. This communication is often …

Fibrinogen plays a central role in the mechanism of coagulation and thrombosis and is
partially involved in the development of postintervention restenosis. Because of therapeutic …

Blood coagulation and platelet adhesion remain major impediments to the use of
biomaterials in implantable medical devices. There is still significant controversy and …

Atomic force microscopy (AFM) was used to directly measure the adhesion forces between
three test proteins and low density polyethylene (LDPE) surfaces treated by glow discharge …

The molecular level details of the displacement of surface adsorbed fibrinogen from silica
substrates were studied by atomic force microscopy, immunochemical assays, fluorescence …

The use of atomic force microscopy (AFM) in biomaterials science and engineering
applications has increased rapidly over the last few years. Beyond being merely a tool for …

Percutaneous or transcutaneous devices are important and unique, and the corresponding
biological sealing at the skin-implant interface is the key to their long-term success. Herein …

Enzymes and biochemical mechanisms essential to survival are under extreme selective
pressure and are highly conserved through evolutionary time. We applied this evolutionary …

Fibrinogen is a major plasma protein. Previous investigations of structural changes of
fibrinogen due to adsorption are mostly based on indirect evidence after its desorption …

Conformational changes of proteins adsorbing on biomaterial surfaces affect
biocompatibility. Titanium is among the most successful biomaterials; however, the …