The Absence of CD4+ T Cell Count Recovery Despite Receipt of Virologically Suppressive Highly Active Antiretroviral Therapy: Clinical Risk, Immunological Gaps …

L Gazzola, C Tincati, GM Bellistré… - Clinical Infectious …, 2009 - academic.oup.com
Up to 30% of human immunodeficiency virus (HIV)–infected patients who are receiving long-
term highly active antiretroviral therapy do not exhibit a marked increase in the CD4+ T cell …

[PDF][PDF] Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART

F Aiuti, I Mezzaroma - Aids Rev, 2006 - researchgate.net
HAART in HIV-1-infected individuals has a broad spectrum of clinical outcomes. In the
majority of patients, plasma viral load becomes undetectable and CD4+ T-cells increase …

[HTML][HTML] Effect of early versus deferred antiretroviral therapy for HIV on survival

MM Kitahata, SJ Gange, AG Abraham… - … England Journal of …, 2009 - Mass Medical Soc
Background The optimal time for the initiation of antiretroviral therapy for asymptomatic
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …

CD4+ Cell Count 6 Years after Commencement of Highly Active Antiretroviral Therapy in Persons with Sustained Virologic Suppression

RD Moore, JC Keruly - Clinical infectious diseases, 2007 - academic.oup.com
Background. Sustained suppression of the human immunodeficiency virus (HIV) type 1 RNA
load with the use of highly active antiretroviral therapy (HAART) results in immunologic …

Continued high prevalence and adverse clinical impact of human immunodeficiency virus–associated sensory neuropathy in the era of combination antiretroviral …

RJ Ellis, D Rosario, DB Clifford, JC McArthur… - Archives of …, 2010 - jamanetwork.com
Objective To provide updated estimates of the prevalence and clinical impact of human
immunodeficiency virus− associated sensory neuropathy (HIV-SN) and neuropathic pain …

[HTML][HTML] Enhanced T cell recovery in HIV-1–infected adults through IL-7 treatment

Y Levy, C Lacabaratz, L Weiss, JP Viard… - The Journal of …, 2009 - Am Soc Clin Investig
HIV infection results in CD4+ T cell deficiency, but efficient combination antiretroviral therapy
(c-ART) restores T cells and decreases morbidity and mortality. However, immune …

Incidence and risk factors for immune reconstitution inflammatory syndrome in an ethnically diverse HIV type 1–infected cohort

I Ratnam, C Chiu, NB Kandala… - Clinical Infectious …, 2006 - academic.oup.com
Background. It is estimated that 10%–25% of patients who start highly active antiretroviral
therapy (HAART) experience immune reconstitution inflammatory syndrome (IRIS). Our …

Long-term mortality in HIV-positive individuals virally suppressed for> 3 years with incomplete CD4 recovery

FN Engsig, R Zangerle, O Katsarou… - Clinical infectious …, 2014 - academic.oup.com
Background. Some human immunodeficiency virus (HIV)–infected individuals initiating
combination antiretroviral therapy (cART) with low CD4 counts achieve viral suppression but …

Response to combination antiretroviral therapy: variation by age

Collaboration of Observational HIV Epidemiological … - Aids, 2008 - journals.lww.com
Objective: To provide information on responses to combination antiretroviral therapy in
children, adolescents and older HIV-infected persons. Design and setting: Multicohort …

Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV

S Grabar, I Kousignian, A Sobel, P Le Bras, J Gasnault… - Aids, 2004 - journals.lww.com
Objective: To study immunologic and clinical responses to HAART in patients over 50 years
old. Design and methods: A prospective cohort study which included 68 hospitals in France …