Genetics of human brain development
Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …
the mechanisms of which remain largely elusive. Recently, integration of technological …
New insights into the development of the human cerebral cortex
The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …
presumed to be responsible for the neuronal computations underlying complex phenomena …
[HTML][HTML] Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
Neurological complications are common in patients with COVID-19. Although severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
The use of brain organoids to investigate neural development and disease
E Di Lullo, AR Kriegstein - Nature Reviews Neuroscience, 2017 - nature.com
Understanding the development and dysfunction of the human brain is a major goal of
neurobiology. Much of our current understanding of human brain development has been …
neurobiology. Much of our current understanding of human brain development has been …
[HTML][HTML] Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure
Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new
platform to investigate human brain development. High cost, variability, and tissue …
platform to investigate human brain development. High cost, variability, and tissue …
Zika virus and birth defects—reviewing the evidence for causality
Zika Virus and Birth Defects — Reviewing the Evidence for Causality | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians
CA Moore, JE Staples, WB Dobyns, A Pessoa… - JAMA …, 2017 - jamanetwork.com
Importance Zika virus infection can be prenatally passed from a pregnant woman to her
fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause …
fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause …
[HTML][HTML] An update on Zika virus infection
The epidemic history of Zika virus began in 2007, with its emergence in Yap Island in the
western Pacific, followed in 2013–14 by a larger epidemic in French Polynesia, south …
western Pacific, followed in 2013–14 by a larger epidemic in French Polynesia, south …
[HTML][HTML] The Brazilian Zika virus strain causes birth defects in experimental models
Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flaviviridae) and
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …
[HTML][HTML] The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …