Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Vitamin B12, also known as the anti-pernicious anemia factor, is an essential micronutrient
totally dependent on dietary sources that is commonly integrated with food supplements …

Ring-opening of epoxides furnishing either linear or branched products belongs to the group
of classic transformations in organic synthesis. However, the regioselective cross …

Biologically active derivatives of vitamin B12 are organometallic cobalt-corrinoid complexes
crucial for the healthy function of humans, animals and microbes. Their role as cofactors to …

First-row transition-metal complexes often show a propensity for forming reactive radical
species, such as superoxide complexes (M–O2·) generated by the binding of O2 to the metal …

This Perspective Article highlights recent theoretical developments, and summarizes the
current understanding of the photolytic properties of cobalamins from a computational point …

The biologically active forms of vitamin B 12, methylcobalamin (MeCbl) and
adenosylcobalamin (AdoCbl), are important cofactors in a variety of enzymatic processes. In …

Cobalamins are of widespread importance in biology. Both of the cofactors essential for
human metabolism, the organocobalamins coenzyme B12 and methylcobalamin, are highly …

Methylcobalamin (MeCbl)-dependent enzyme methionine synthase (MetH), plays a critical
role in the catalysis of methyl group transfer from methyltetrahydrofolate (CH 3-H 4 folate) to …

The discovery of naturally occurring B 12-depedent photoreceptors has allowed for
applications of cobalamins (Cbls) in optogenetics and synthetic biology to emerge …