Looking beyond Saccharomyces: the potential of non-conventional yeast species for desirable traits in bioethanol fermentation

D Radecka, V Mukherjee, RQ Mateo… - FEMS yeast …, 2015 - academic.oup.com
Saccharomyces cerevisiae has been used for millennia in the production of food and
beverages and is by far the most studied yeast species. Currently, it is also the most used …

Microbial heterogeneity affects bioprocess robustness: Dynamic single‐cell analysis contributes to understanding of microbial populations

F Delvigne, P Goffin - Biotechnology journal, 2014 - Wiley Online Library
Heterogeneity or segregation of microbial populations has been the subject of much
research, but the real impact of this phenomenon on bioprocesses remains poorly …

[HTML][HTML] Biological Parts for Kluyveromyces marxianus Synthetic Biology

AS Rajkumar, JA Varela, H Juergens… - … in bioengineering and …, 2019 - frontiersin.org
Kluyveromyces marxianus is a non-conventional yeast whose physiology and metabolism
lends itself to diverse biotechnological applications. While the wild-type yeast is already in …

[HTML][HTML] CRISPR–Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus

AK Löbs, R Engel, C Schwartz, A Flores… - Biotechnology for …, 2017 - Springer
Abstract Background The thermotolerant yeast Kluyveromyces marxianus shows promise as
an industrial host for the biochemical production of fuels and chemicals. Wild-type strains …

Cell factory applications of the yeast Kluyveromyces marxianus for the biotechnological production of natural flavour and fragrance molecules

JP Morrissey, MMW Etschmann, J Schrader… - Yeast, 2015 - Wiley Online Library
Kluyveromyces marxianus is emerging as a new platform organism for the production of
flavour and fragrance (F&F) compounds. This food‐grade yeast has advantageous traits …

Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity

F Delvigne, Q Zune, AR Lara, W Al-Soud… - Trends in …, 2014 - cell.com
Phenotypic heterogeneity is a major issue in the context of industrial bioprocessing.
Stochasticity of gene expression is usually considered to be the main source of …

[HTML][HTML] CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus

M Li, X Lang, M Moran Cabrera, S De Keyser… - Biotechnology for …, 2021 - Springer
Abstract Background 2-phenylethanol (2-PE) is a rose-scented flavor and fragrance
compound that is used in food, beverages, and personal care products. Compatibility with …

Kluyveromyces as promising yeast cell factories for industrial bioproduction: From bio-functional design to applications

Y Qiu, P Lei, R Wang, L Sun, Z Luo, S Li, H Xu - Biotechnology Advances, 2023 - Elsevier
As the two most widely used Kluyveromyces yeast, Kluyveromyces marxianus and K. lactis
have gained increasing attention as microbial chassis in biocatalysts, biomanufacturing and …

Biosynthesis of 2-phenylethanol from glucose with genetically engineered Kluyveromyces marxianus

TY Kim, SW Lee, MK Oh - Enzyme and Microbial Technology, 2014 - Elsevier
Phenylethanol (2-PE) is an aromatic alcohol with a rose scent, which is used in the
cosmetics, fragrance and food industries. 2-PE is produced in a few yeast strains by Ehrlich …

A biosynthetic pathway for hexanoic acid production in Kluyveromyces marxianus

Y Cheon, JS Kim, JB Park, P Heo, JH Lim… - Journal of …, 2014 - Elsevier
Hexanoic acid can be used for diverse industrial applications and is a precursor for fine
chemistry. Although some natural microorganisms have been screened and evolved to …