[HTML][HTML] Pregnancy-related maternal physiological adaptations and fetal chemical exposure
MT Vinnars, M Bixo, P Damdimopoulou - Molecular and Cellular …, 2023 - Elsevier
Prenatal life represents a susceptible window of development during which chemical
exposures can permanently alter fetal development, leading to an increased likelihood of …
exposures can permanently alter fetal development, leading to an increased likelihood of …
Non‐Viral RNA Delivery During Pregnancy: Opportunities and Challenges
N Chaudhary, AN Newby, KA Whitehead - Small, 2023 - Wiley Online Library
During pregnancy, the risk of maternal and fetal adversities increases due to physiological
changes, genetic predispositions, environmental factors, and infections. Unfortunately …
changes, genetic predispositions, environmental factors, and infections. Unfortunately …
Young-onset breast cancer outcomes by time since recent childbirth in Utah
Importance Breast cancer diagnosed within 5 to 10 years after childbirth, calledpostpartum
breast cancer (PPBC), is associated with increased risk for metastasis and death. Whether a …
breast cancer (PPBC), is associated with increased risk for metastasis and death. Whether a …
Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing
S He, Z Guo, M Zhou, H Wang, Z Zhang, M Shi, X Li… - Cell Stem Cell, 2023 - cell.com
The maternal liver undergoes dramatic enlargement to adapt to the increased metabolic
demands during pregnancy. However, the cellular sources for liver growth during pregnancy …
demands during pregnancy. However, the cellular sources for liver growth during pregnancy …
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress
Maternal obesity (MO) is rising worldwide, affecting half of all gestations, constituting a
possible risk-factor for some pregnancy-associated liver diseases (PALD) and hepatic …
possible risk-factor for some pregnancy-associated liver diseases (PALD) and hepatic …
Adipose tissue-liver cross-talk: a route to hepatic dysfunction in pregnant women with obesity
D Sousa, CC Magalhães, P Matafome… - Bioscience …, 2024 - portlandpress.com
Obesity during pregnancy has been escalating, becoming a huge problem that poses
consequences not only for the health of the offspring but also for the maternal well-being …
consequences not only for the health of the offspring but also for the maternal well-being …
A multi-tissue metabolome atlas of primate pregnancy
D Yu, H Wan, C Tong, L Guang, G Chen, J Su, L Zhang… - Cell, 2024 - cell.com
Pregnancy induces dramatic metabolic changes in females; yet, the intricacies of this
metabolic reprogramming remain poorly understood, especially in primates. Using …
metabolic reprogramming remain poorly understood, especially in primates. Using …
Periportal hepatocyte proliferation at midgestation governs maternal glucose homeostasis in mice
S Kozuki, M Kabata, S Sakurai, K Iwaisako… - Communications …, 2023 - nature.com
The maternal liver is challenged by metabolic demands throughout pregnancy. However,
hepatocyte dynamics and their physiological significance in pregnancy remain unclear …
hepatocyte dynamics and their physiological significance in pregnancy remain unclear …
[HTML][HTML] The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway
Background: Hepatotoxicity caused by CCL 4 is well known. Geraniol (GNL) has high
antioxidant effect that can induces liver regeneration. However, the protective effect of GNL …
antioxidant effect that can induces liver regeneration. However, the protective effect of GNL …
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses
D Yu, L Luo, H Wang, N Shyh-Chang - Trends in Endocrinology & …, 2024 - cell.com
Pregnancy is associated with physiological adaptations that affect virtually all organs,
enabling the mother to support the growing fetus and placenta while withstanding the …
enabling the mother to support the growing fetus and placenta while withstanding the …