Platelets, key facilitators of primary hemostasis and thrombosis, have emerged as crucial
cellular mediators of innate immunity and inflammation. Exemplified by their ability to alter …

This review focuses on the immunosuppressive effects of tumor angiogenesis and
coagulation on the tumor microenvironment (TME). We summarize previous research efforts …

Background Platelet count (PLT) is associated positively with lung cancer risk but has a
more complex association with body mass index (BMI), positive only in women (mainly …

This study aimed to evaluate the correlation between the pre-treatment peripheral platelet-to-
lymphocyte ratio (PLR) and the prognostic nutritional index (PNI) with the efficacy and …

Among multiple hemostasis components, platelets hyperactivity plays major roles in cancer
progression by providing surface and internal components for intercellular crosstalk as well …

Problem The occurrence of preterm birth is associated with multiple factors including
bleeding, infection and inflammation. Platelets are mediators of hemostasis and can …

Studies have shown that elevated plasma levels of platelet-derived soluble TREM-like
transcript-1 (sTLT-1) are associated with an unfavorable outcome in patients with septic …

Lipid remodeling, from fatty acid transport and de novo lipid synthesis, is necessary for
megakaryocyte differentiation and platelet production. Dietary saturated fatty acids, impaired …

There are circumstances where tumors can only be partially resected. Therefore,
multimodality therapy targeting post-operative residuals is important. Here, we show that …

Background Ischemic stroke (IS), caused by blood and oxygen deprivation due to cerebral
thrombosis, has links to activated and aggregated platelets. Discovering platelet-related …