Current understanding of the role of nesfatin-1

MA Schalla, A Stengel - Journal of the endocrine society, 2018 - academic.oup.com
Nesfatin-1 was discovered in 2006 and implicated in the regulation of food intake.
Subsequently, its widespread central and peripheral distribution gave rise to additional …

Nesfatin-1–More than a food intake regulatory peptide

A Stengel - Peptides, 2015 - Elsevier
Nesfatin-1 was discovered a decade ago and despite the fact that it represents just one of a
multitude of food intake-inhibiting factors it received increasing attention. This led to a …

Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double …

SA Jazayeri-Tehrani, SM Rezayat, S Mansouri… - Nutrition & …, 2019 - Springer
Background Since lifestyle changes are main therapies for non-alcoholic fatty liver disease
(NAFLD), changing dietary components (nutritional or bioactive) may play a parallel …

Nesfatin-1 in human and murine cardiomyocytes: synthesis, secretion, and mobilization of GLUT-4

S Feijóo-Bandín, D Rodríguez-Penas… - …, 2013 - academic.oup.com
Nesfatin-1, a satiety-inducing peptide identified in hypothalamic regions that regulate energy
balance, is an integral regulator of energy homeostasis and a putative glucose-dependent …

The role of nesfatin‐1 in the regulation of food intake and body weight: recent developments and future endeavors

A Stengel, M Mori, Y Taché - Obesity Reviews, 2013 - Wiley Online Library
Nesfatin‐1 was discovered in 2006 and introduced as a potential novel anorexigenic
modulator of food intake and body weight. The past years have witnessed increasing …

Multi-functional peptide hormone NUCB2/nesfatin-1

S Aydin - Endocrine, 2013 - Springer
The recently discovered nesfatin-1 is regulated by hunger and satiety. The precursor protein
NUCB2 is proteolytically cleaved into three resulting fragments: nesfatin-1, nesfatin-2, and …

Impact of nonalcoholic fatty liver disease-related metabolic state on depression

S Ntona, A Papaefthymiou, J Kountouras… - Neurochemistry …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), also recently referred as metabolic (dysfunction)-
associated fatty liver disease (MAFLD), is characterized by hepatocyte steatosis in the …

NUCB2/nesfatin-1 is associated with elevated levels of anxiety in anorexia nervosa

T Hofmann, A Ahnis, U Elbelt, M Rose, BF Klapp… - PLoS …, 2015 - journals.plos.org
Objective NUCB2/nesfatin-1 is an anorexigenic hormone with elevated levels in obese and
decreased levels in anorexia nervosa (AN) patients. Moreover, a role in the regulation of …

AMPK-dependent modulation of hepatic lipid metabolism by nesfatin-1

Y Yin, Z Li, L Gao, Y Li, J Zhao, W Zhang - Molecular and cellular …, 2015 - Elsevier
The aim of this study was to characterize the mechanism by which peripheral nesfatin-1
regulates hepatic lipid metabolism. Continuous peripheral infusion of nesfatin-1 reduced …

Sex-specific regulation of NUCB2/nesfatin-1: Differential implication in anxiety in obese men and women

T Hofmann, U Elbelt, A Ahnis, M Rose, BF Klapp… - …, 2015 - Elsevier
Nesfatin-1 is cleaved from nucleobindin2 (NUCB2) and implicated in the regulation of
hunger and satiety as anorexigenic peptide hormone. Circulating NUCB2/nesfatin-1 is …