Chronic wounds
V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …
and have emerged as an increasingly important clinical problem over the past several …
Breakthrough treatments for accelerated wound healing
BR Freedman, C Hwang, S Talbot, B Hibler… - Science …, 2023 - science.org
Skin injuries across the body continue to disrupt everyday life for millions of patients and
result in prolonged hospital stays, infection, and death. Advances in wound healing devices …
result in prolonged hospital stays, infection, and death. Advances in wound healing devices …
Osteoimmunity‐regulating biomimetically hierarchical scaffold for augmented bone regeneration
J Zhang, D Tong, H Song, R Ruan, Y Sun… - Advanced …, 2022 - Wiley Online Library
Engineering a proper immune response following biomaterial implantation is essential to
bone tissue regeneration. Herein, a biomimetically hierarchical scaffold composed of …
bone tissue regeneration. Herein, a biomimetically hierarchical scaffold composed of …
The role of oxidative stress and antioxidants in diabetic wound healing
L Deng, C Du, P Song, T Chen, S Rui… - Oxidative medicine …, 2021 - Wiley Online Library
Foot ulcers are one of the most common and severe complication of diabetes mellitus with
significant resultant morbidity and mortality. Multiple factors impair wound healing include …
significant resultant morbidity and mortality. Multiple factors impair wound healing include …
[HTML][HTML] Deferoxamine B: a natural, excellent and versatile metal chelator
D Bellotti, M Remelli - Molecules, 2021 - mdpi.com
Deferoxamine B is an outstanding molecule which has been widely studied in the past
decade for its ability to bind iron and many other metal ions. The versatility of this metal …
decade for its ability to bind iron and many other metal ions. The versatility of this metal …
[HTML][HTML] Electrospun nanofibers/nanofibrous scaffolds loaded with silver nanoparticles as effective antibacterial wound dressing materials
S Alven, B Buyana, Z Feketshane, BA Aderibigbe - Pharmaceutics, 2021 - mdpi.com
The treatment of wounds is expensive and challenging. Most of the available wound
dressings are not effective and suffer from limitations such as poor antimicrobial activity …
dressings are not effective and suffer from limitations such as poor antimicrobial activity …
Calcium ion cross-linked sodium alginate hydrogels containing deferoxamine and copper nanoparticles for diabetic wound healing
S Li, X Wang, J Chen, J Guo, M Yuan, G Wan… - International Journal of …, 2022 - Elsevier
Chronic non-healing diabetic wounds and ulcers can be fatal, lead to amputations, and
remain a major challenge to medical, and health care sectors. Susceptibility to infection and …
remain a major challenge to medical, and health care sectors. Susceptibility to infection and …
Oriented nanofibrous P (MMD-co-LA)/Deferoxamine nerve scaffold facilitates peripheral nerve regeneration by regulating macrophage phenotype and …
Delayed injured nerve regeneration remains a clinical problem, partly ascribing to the lack of
regulation of regenerative microenvironment, topographical cues, and blood nourishment …
regulation of regenerative microenvironment, topographical cues, and blood nourishment …
Challenges and opportunities of deferoxamine delivery for treatment of Alzheimer's disease, Parkinson's disease, and intracerebral hemorrhage
AC Farr, MP Xiong - Molecular pharmaceutics, 2020 - ACS Publications
Deferoxamine mesylate (DFO) is an FDA-approved, hexadentate iron chelator routinely
used to alleviate systemic iron burden in thalassemia major and sickle cell patients. Iron …
used to alleviate systemic iron burden in thalassemia major and sickle cell patients. Iron …
Autophagosomes Defeat Ferroptosis by Decreasing Generation and Increasing Discharge of Free Fe2+ in Skin Repair Cells to Accelerate Diabetic Wound Healing
S Cui, X Liu, Y Liu, W Hu, K Ma, Q Huang… - Advanced …, 2023 - Wiley Online Library
Ferroptosis plays an essential role in the development of diabetes and its complications,
suggesting potential therapeutic strategies targeting ferroptosis. Secretory autophagosomes …
suggesting potential therapeutic strategies targeting ferroptosis. Secretory autophagosomes …