Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

Immunosuppressive drugs have revolutionized organ transplantation and improved the
therapeutic management of autoimmune diseases. The development of immunosuppressive …

Specific therapy with modulated DC may restore immunological tolerance, thereby obviating
the need for chronic immunosuppression in transplantation or autoimmunity. In this study we …

Dendritic cells (DCs) play a central role in regulating immune activation and responses to
self. DC maturation is central to the outcome of antigen presentation to T cells. Maturation of …

Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive agents which
exert multiple effects on immune cell functions. Although their use dates back 60years, their …

Several studies have demonstrated unequivocally that certain nonsteroidal anti‐
inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and …

The dendritic cell (DC) system of antigen‐presenting cells controls immunity and tolerance.
DCs initiate and regulate immune responses in a manner that depends on signals they …

Glucocorticoids are steroid hormones that regulate diverse cellular functions and are
essential to facilitate normal physiology. However, stress-induced levels of glucocorticoids …

We recognize well the abilities of dendritic cells to activate effector T cell (Teff cell)
responses to an array of antigens and think of these cells in this context as pre-eminent …

The serum opsonin mannose‐binding lectin (MBL) has been shown to be involved in the
handling of apoptotic cells. However, at what stage in the process this happens and whether …