White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small
vessel disease, and can easily be detected on MRI. Over the past three decades, research …

Transcranial magnetic stimulation (TMS) is a powerful tool to probe in vivo brain circuits, as it
allows to assess several cortical properties such as excitability, plasticity and connectivity in …

Vascular cognitive impairment (VCI)[vascular cognitive disorder (VCD), vascular dementia]
describes a continuum of cognitive disorders ranging from mild cognitive impairment (MCI) …

Delirium is a common and serious acute neuropsychiatric syndrome with core features of
inattention and cognitive impairment, and associated features including changes in arousal …

Vascular cognitive impairment (VCI) comprises a range of cognitive disorders related to
cerebral vessel disease and has generally replaced the term multi-infarct dementia. Despite …

Diffusion tensor imaging (DTI) can detect, in vivo, the directionality of molecular diffusion and
estimate the microstructural integrity of white matter (WM) tracts. In this study, we examined …

Background and Purpose—Clinical observations suggest that patients with vascular
dementia (VaD) may benefit from treatment with cholinesterase inhibitors. This study …

Background—Cerebrovascular disease (CVD) and ischemic brain injury secondary to
cardiovascular disease are common causes of dementia and cognitive decline in the …

Alzheimer's disease (AD) is characterized by progressive, age-dependent degeneration of
neurons in the central nervous system. A large body of evidence indicates that neurons …

Background Cholinergic deficits might contribute to vascular cognitive impairment. Trials of
cholinesterase inhibitors in patients with vascular dementia are difficult because of …