Autophagy in liver diseases: a review

H Qian, X Chao, J Williams, S Fulte, T Li, L Yang… - Molecular aspects of …, 2021 - Elsevier
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

Thiram exposure in environment: A critical review on cytotoxicity

K Liu, Y Li, M Iqbal, Z Tang, H Zhang - Chemosphere, 2022 - Elsevier
Thiram is used in large quantities in agriculture and may contaminate the environment by
improper handling or storage in chemical plants and warehouses. A review of the literature …

[HTML][HTML] Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies

C Yao, S Dai, C Wang, K Fu, R Wu, X Zhao… - Biomedicine & …, 2023 - Elsevier
Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

[HTML][HTML] Targeting autophagy using long non-coding RNAs (LncRNAs): new landscapes in the arena of cancer therapeutics

A Kumar, S Girisa, MS Alqahtani, M Abbas, M Hegde… - Cells, 2023 - mdpi.com
Cancer has become a global health hazard accounting for 10 million deaths in the year
2020. Although different treatment approaches have increased patient overall survival …

AMPK/mTOR pathway significance in healthy liver and non‐alcoholic fatty liver disease and its progression

IA Marcondes‐de‐Castro… - Journal of …, 2023 - Wiley Online Library
Obesity is related to several organs, but the liver is particularly affected. Adenosine
monophosphate‐activated protein kinase (AMPK) is a cellular energy sensor and regulator …

Cold exposure‐induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway

J Guo, J Nie, Z Chen, X Wang, H Hu… - Journal of Cellular …, 2022 - Wiley Online Library
Cold is a factor affecting health in humans and animals. The liver, a major metabolic center,
is highly susceptible to ambient air temperature. Recent studies have shown that …

[HTML][HTML] Metformin and dichloroacetate suppress proliferation of liver cancer cells by inhibiting mTOR complex 1

TS Kim, M Lee, M Park, SY Kim, MS Shim… - International Journal of …, 2021 - mdpi.com
The Warburg effect is important for cancer cell proliferation. This phenomenon can be
flexible by interaction between glycolysis and mitochondrial oxidation for energy production …

p62/SQSTM1 in liver diseases: the usual suspect with multifarious identities

CT Tan, NJH Soh, HC Chang, VC Yu - The FEBS journal, 2023 - Wiley Online Library
p62/Sequestosome‐1 (SQSTM1) is a selective autophagy receptor that recruits and delivers
intracellular substrates for bulk clearance through the autophagy lysosomal pathway …

[HTML][HTML] Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy

Y Tang, L Wang, T Yi, J Xu, J Wang, JJ Qin… - … Pharmaceutica Sinica B, 2021 - Elsevier
Mitochondria as a signaling platform play crucial roles in deciding cell fate. Many classic
anticancer agents are known to trigger cell death through induction of mitochondrial …

Autophagy regulation in teleost fish: A double-edged sword

Z Zhou, Y He, S Wang, Y Wang, P Shan, P Li - Aquaculture, 2022 - Elsevier
In the last two decades, autophagy has attracted considerable attention as a conserved
cellular self-digestion process that is essential for cells to maintain metabolism and energy …