The term monoclonal gammopathy of renal significance (MGRS) was introduced by the
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …

Treatment of multiple myeloma has substantially changed over the past decade with the
introduction of several classes of new effective drugs that have greatly improved the rates …

Abstract Disease Overview Multiple myeloma accounts for approximately 10% of
hematologic malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow …

Multiple myeloma is a malignant neoplasm of plasma cells that accumulate in bone marrow,
leading to bone destruction and marrow failure. This manuscript discusses the management …

Summary This International Myeloma Working Group consensus updates the disease
definition of multiple myeloma to include validated biomarkers in addition to existing …

Multiple myeloma accounts for approximately 10% of hematologic malignancies. The
diagnosis requires≥ 10% clonal bone marrow plasma cells or a biopsy proven …

Abstract Disease Overview Immunoglobulin light chain amyloidosis is a clonal,
nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy …

Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused
by a monoclonal immunoglobulin (MIg) secreted by a nonmalignant B-cell clone. By …

Disease overview Multiple myeloma accounts for approximately 10% of hematologic
malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow plasma cells or …

Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal
immunoglobulin (M-protein) which they produce. Traditionally, serum protein …