[PDF][PDF] The immunology of sepsis
T van der Poll, M Shankar-Hari, WJ Wiersinga - Immunity, 2021 - cell.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. This recently implemented definition does not capture the …
response to an infection. This recently implemented definition does not capture the …
[HTML][HTML] Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …
strongly associated with adverse outcomes, including an increased risk of chronic kidney …
[HTML][HTML] Restriction of intravenous fluid in ICU patients with septic shock
TS Meyhoff, PB Hjortrup, J Wetterslev… - … England Journal of …, 2022 - Mass Medical Soc
Background Intravenous fluids are recommended for the treatment of patients who are in
septic shock, but higher fluid volumes have been associated with harm in patients who are …
septic shock, but higher fluid volumes have been associated with harm in patients who are …
[HTML][HTML] Early restrictive or liberal fluid management for sepsis-induced hypotension
National Heart, Lung, and Blood Institute … - … England Journal of …, 2023 - Mass Medical Soc
Background Intravenous fluids and vasopressor agents are commonly used in early
resuscitation of patients with sepsis, but comparative data for prioritizing their delivery are …
resuscitation of patients with sepsis, but comparative data for prioritizing their delivery are …
Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …
L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …
mortality worldwide, and its importance is further emphasized in the context of the novel …
[HTML][HTML] Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a …
Purpose Insufficient antimicrobial exposure is associated with worse outcomes in sepsis. We
evaluated whether therapeutic drug monitoring (TDM)-guided antibiotic therapy improves …
evaluated whether therapeutic drug monitoring (TDM)-guided antibiotic therapy improves …
[HTML][HTML] Bias in artificial intelligence algorithms and recommendations for mitigation
LH Nazer, R Zatarah, S Waldrip, JXC Ke… - PLOS digital …, 2023 - journals.plos.org
The adoption of artificial intelligence (AI) algorithms is rapidly increasing in healthcare. Such
algorithms may be shaped by various factors such as social determinants of health that can …
algorithms may be shaped by various factors such as social determinants of health that can …
[HTML][HTML] How to use biomarkers of infection or sepsis at the bedside: guide to clinicians
P Póvoa, L Coelho, F Dal-Pizzol, R Ferrer… - Intensive care …, 2023 - Springer
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …
response to infection. In this context, biomarkers could be considered as indicators of either …
[HTML][HTML] How can assessing hemodynamics help to assess volume status?
In critically ill patients, fluid infusion is aimed at increasing cardiac output and tissue
perfusion. However, it may contribute to fluid overload which may be harmful. Thus, volume …
perfusion. However, it may contribute to fluid overload which may be harmful. Thus, volume …