The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

This review aims to assess different technologies for the on-site treatment of hospital
wastewater (HWW) to remove pharmaceutical compounds (PhCs) as sustances of emerging …

Antibiotic resistance (ABR) is recognized as a One Health challenge because of the rapid
emergence and dissemination of resistant bacteria and genes among humans, animals and …

Water environments are increasingly recognized as a conduit for the spread of antibiotic
resistance, but there is need to standardize antibiotic resistance monitoring protocols to …

Antimicrobial resistance is an urgent global health challenge in human and veterinary
medicine. Wild animals are not directly exposed to clinically relevant antibiotics; however …

Purpose High antibiotic and antifungal concentrations in wastewater from anti-infective drug
production may exert selection pressure for multidrug-resistant (MDR) pathogens. We …

The hospital environment is a potential reservoir of bacteria with plasmids conferring
carbapenem resistance. Our Hospital Epidemiology Service routinely performs extensive …

Background OqxAB efflux pump has been found to mediate multidrug resistance (MDR) in
various bacteria over the past decades. The updates on the nature and epidemiology of …

Antibiotic resistance is one of the greatest public-health challenges worldwide, especially
with regard to Gram-negative bacteria (GNB). Carbapenems are the β-lactam antibiotics of …

Carbapenems are the decision-making antimicrobials used to combat severe Gram-
negative bacterial infections in humans. Carbapenem resistance poses a potential public …