[HTML][HTML] Equivocal, explicit and emergent actions of PKC isoforms in cancer
PJ Parker, SJ Brown, V Calleja, P Chakravarty… - Nature Reviews …, 2021 - nature.com
The maturing mutational landscape of cancer genomes, the development and application of
clinical interventions and evolving insights into tumour-associated functions reveal …
clinical interventions and evolving insights into tumour-associated functions reveal …
[HTML][HTML] The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells.
D Heffetz, I Bushkin, R Dror, Y Zick - Journal of Biological Chemistry, 1990 - Elsevier
H2O2 and vanadate are known insulinomimetic agents. Together they induce insulin's
bioeffects with a potency which exceeds that seen with insulin, vanadate, or H2O2 alone …
bioeffects with a potency which exceeds that seen with insulin, vanadate, or H2O2 alone …
Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate in vitro
D Hecht, Y Zick - Biochemical and biophysical research communications, 1992 - Elsevier
Abstract Acute (10–30 min) treatment of intact rat hepatoma (Fao) cells with H 2 O 2, inhibits
in vivo protein tyrosine phosphatase activity. Vanadate markedly potentiates this effect …
in vivo protein tyrosine phosphatase activity. Vanadate markedly potentiates this effect …
Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in …
A Clerk, MA Bogoyevitch, MB Anderson… - Journal of Biological …, 1994 - ASBMB
The translocation of protein kinase C (PKC) isoforms PKC-alpha, PKC-delta, PKC-epsilon,
and PKC-zeta from soluble to particulate fractions was studied in ventricular cardiomyocytes …
and PKC-zeta from soluble to particulate fractions was studied in ventricular cardiomyocytes …
Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters …
MA Bogoyevitch, PJ Parker, PH Sugden - Circulation research, 1993 - Am Heart Assoc
The pattern of protein kinase C (PKC) isotype expression in whole extracts of dispersed,
freshly isolated adult rat ventricular myocytes and adult rat heart ventricle was examined by …
freshly isolated adult rat ventricular myocytes and adult rat heart ventricle was examined by …
Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells
RL Whisler, MA Goyette, IS Grants… - Archives of biochemistry …, 1995 - Elsevier
Sublethal concentrations of reactive oxygen intermediates including H2O2 can alter human
T cell function and inhibit proliferative responses but relatively little is known about the …
T cell function and inhibit proliferative responses but relatively little is known about the …
Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ.
ML Saxon, X Zhao, JD Black - The Journal of cell biology, 1994 - rupress.org
The mechanisms underlying control of cell growth and differentiation in epithelial tissues are
poorly understood. Protein kinase C (PKC) isozymes, members of a large family of …
poorly understood. Protein kinase C (PKC) isozymes, members of a large family of …
Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
A Kazlauskas, JA Cooper - The Journal of cell biology, 1988 - rupress.org
One of the early events after stimulation of Swiss 3T3 cells with either platelet-derived
growth factor (PDGF), 12-O-tetradecanoyl-phorbol-13-acetate (TPA), diacylglycerol, or …
growth factor (PDGF), 12-O-tetradecanoyl-phorbol-13-acetate (TPA), diacylglycerol, or …
Regulation of protein kinase C by nerve growth factor, epidermal growth factor, and phorbol esters in PC12 pheochromocytoma cells
LE Heasley, GL Johnson - Journal of Biological Chemistry, 1989 - Elsevier
We have used a permeabilized cell assay and a synthetic peptide substrate (KRTLRR) to
specifically monitor the activity of protein kinase C in PC12 cells preincubated with nerve …
specifically monitor the activity of protein kinase C in PC12 cells preincubated with nerve …
Protein kinase C: subcellular redistribution by increased Ca2+ influx. Evidence that Ca2+-dependent subcellular redistribution of protein kinase C is involved in …
AK Ho, TP Thomas, CL Chik, WB Anderson… - Journal of Biological …, 1988 - ASBMB
Phenylephrine is known to stimulate translocation of protein kinase C in rat pinealocytes
(Sugden, D., Vanecek, J., Klein, DC, Thomas, TP, and Anderson, WB (1985) Nature 314 …
(Sugden, D., Vanecek, J., Klein, DC, Thomas, TP, and Anderson, WB (1985) Nature 314 …