Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

Anticancer potential of flavonoids: an overview with an emphasis on tangeretin

FCF de Luna, WAS Ferreira, SMM Casseb… - Pharmaceuticals, 2023 - mdpi.com
Natural compounds with pharmacological activity, flavonoids have been the subject of an
exponential increase in studies in the field of scientific research focused on therapeutic …

Crosstalk between methylation and ncRNAs in breast cancer: therapeutic and diagnostic implications

Y Liu, P Leng, Y Liu, J Guo, H Zhou - International Journal of Molecular …, 2022 - mdpi.com
Breast cancer, as a highly heterogeneous malignant tumor, is one of the primary causes of
death among females worldwide. The etiology of breast cancer involves aberrant epigenetic …

Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy

Q Yang, S Zeng, W Liu - PeerJ, 2023 - peerj.com
Background Studies have shown that the expressions and working mechanisms of
Dihydrolipoamide S-acetyltransferase (DLAT) in different cancers vary. It is necessary to …

Rhamnetin, a nutraceutical flavonoid arrests cell cycle progression of human ovarian cancer (SKOV3) cells by inhibiting the histone deacetylase 2 protein

KK Bharadwaj, B Rabha, I Ahmad… - Journal of …, 2023 - Taylor & Francis
Overexpression of HDAC 2 promotes cell proliferation in ovarian cancer. HDAC 2 is involved
in chromatin remodeling, transcriptional repression, and the formation of condensed …

Drought-Adapted Mediterranean Diet Plants: A Source of Bioactive Molecules Able to Give Nutrigenomic Effects per sè or to Obtain Functional Foods

S La Scala, F Naselli, P Quatrini, G Gallo… - International Journal of …, 2024 - mdpi.com
The Mediterranean diet features plant-based foods renowned for their health benefits
derived from bioactive compounds. This review aims to provide an overview of the bioactive …

Flavonoids attenuate cancer metabolism by modulating lipid metabolism, amino acids, ketone bodies and redox state mediated by Nrf2

M Samec, A Mazurakova, V Lucansky… - European Journal of …, 2023 - Elsevier
Metabolic reprogramming of cancer cells is a common hallmark of malignant transformation.
The preference for aerobic glycolysis over oxidative phosphorylation in tumors is a well …

Sinomenine mitigates cisplatin-induced kidney injury by targeting multiple signaling pathways

I Potočnjak, L Šimić, L Batičić, H Križan… - Food and chemical …, 2023 - Elsevier
Sinomenine is a pharmacologically active alkaloid with antioxidant and anti-inflammatory
properties. We aimed to investigate the mechanism of renoprotective activity of sinomenine …

Nutrient-Epigenome interactions: Implications for personalized nutrition against aging-associated diseases

H Missong, R Joshi, N Khullar, S Thareja… - The Journal of …, 2024 - Elsevier
Ageing is a multifaceted process involving genetic and environmental interactions often
resulting in epigenetic changes, potentially leading to ageing-related diseases. Various …

Trained immunity in monocyte/macrophage: Novel mechanism of phytochemicals in the treatment of atherosclerotic cardiovascular disease

J Wang, YM Liu, J Hu, C Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Atherosclerosis (AS) is the pathology of atherosclerotic cardiovascular diseases (ASCVD),
characterized by persistent chronic inflammation in the vessel wall, in which monocytes …