The role of inflammation in the treatment of schizophrenia
Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …
schizophrenia. The objective of the present work was to synthetize in a narrative review the …
Toxoplasmosis and Schizophrenia: A Systematic Review and Meta‐Analysis of Prevalence and Associations and Future Directions
DG Contopoulos‐Ioannidis, M Gianniki… - Psychiatric …, 2022 - Am Psychiatric Assoc
Background A potential link between toxoplasmosis with schizophrenia (SCZ) has been
extensively studied over the past 2 decades. Our study was aimed to determine whether …
extensively studied over the past 2 decades. Our study was aimed to determine whether …
Toxoplasma gondii, Suicidal Behavior, and Intermediate Phenotypes for Suicidal Behavior
Within the general literature on infections and suicidal behavior, studies on Toxoplasma
gondii (T. gondii) occupy a central position. This is related to the parasite's neurotropism …
gondii (T. gondii) occupy a central position. This is related to the parasite's neurotropism …
Estimations of the number people with mental diseases associated with toxoplasmosis and identification of risk factors by continent
J Nessim, JC Luna-Ramirez, GA Moreno-Gómez… - Psychiatry …, 2023 - Elsevier
Strong evidence exists based on metanalysis of the relationship between toxoplasmosis and
many psychiatric diseases: schizophrenia, bipolar disorder, and suicidal behavior. Herein …
many psychiatric diseases: schizophrenia, bipolar disorder, and suicidal behavior. Herein …
Guanabenz reverses a key behavioral change caused by latent toxoplasmosis in mice by reducing neuroinflammation
J Martynowicz, L Augusto, RC Wek, SL Boehm… - MBio, 2019 - Am Soc Microbiol
Toxoplasma gondii is an intracellular parasite that has infected one-third of humans. The
infection is permanent because the replicative form (tachyzoite) converts into a latent tissue …
infection is permanent because the replicative form (tachyzoite) converts into a latent tissue …
Evaluation of long-term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins
M Chyb, B Dziadek, K Dzitko, BT Ferra, M Kawka… - Scientific Reports, 2023 - nature.com
Toxoplasmosis caused by the opportunistic, cosmopolitan protozoan Toxoplasma gondii is
one of the most common parasitoses in the world. Although it may prove dangerous or even …
one of the most common parasitoses in the world. Although it may prove dangerous or even …
Interaction between the complement system and infectious agents–a potential mechanistic link to neurodegeneration and dementia
As part of the innate immune system, complement plays a critical role in the elimination of
pathogens and mobilization of cellular immune responses. In the central nervous system …
pathogens and mobilization of cellular immune responses. In the central nervous system …
Neurological and Neurobehavioral Disorders Associated with Toxoplasma gondii Infection in Humans
MA Virus, EG Ehrhorn, LAM Lui… - Journal of parasitology …, 2021 - Wiley Online Library
The intracellular parasite Toxoplasma gondii is estimated to infect up to 30% of the world
population, leading to lifelong chronic infection of the brain and muscle tissue. Although …
population, leading to lifelong chronic infection of the brain and muscle tissue. Although …
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology
T Mouveaux, E Roger, A Gueye, F Eysert… - Open …, 2021 - royalsocietypublishing.org
Toxoplasma gondii is a eukaryotic parasite that forms latent cysts in the brain of
immunocompetent individuals. The latent parasite infection of the immune-privileged central …
immunocompetent individuals. The latent parasite infection of the immune-privileged central …
Association of T. gondii infection with suicide: a systematic review and meta-analysis
E Soleymani, F Faizi, R Heidarimoghadam… - BMC Public Health, 2020 - Springer
Background Findings on the association between Toxoplasma gondii (T. gondii) infection
and suicide are contradictory. This paper aimed to resolve this uncertainty by conducting a …
and suicide are contradictory. This paper aimed to resolve this uncertainty by conducting a …