[HTML][HTML] The utility of peripheral blood leucocyte ratios as biomarkers in neonatal sepsis: a systematic review and meta-analysis

J Zhang, J Zeng, L Zhang, X Yu, J Guo, Z Li - Frontiers in Pediatrics, 2022 - frontiersin.org
Background Early stage diagnosis of neonatal sepsis (NS) remains a major roadblock due
to non-specific symptoms and the absence of precise laboratory index tests. The full blood …

[HTML][HTML] LPIN1 is a regulatory factor associated with immune response and inflammation in sepsis

W Dai, P Zheng, D Luo, Q Xie, F Liu, Q Shao… - Frontiers in …, 2022 - frontiersin.org
Objectives Sepsis is a clinical disease that is typically treated in the intensive care unit, and
the complex pathophysiology under this disease has not been thoroughly understood. While …

The Sensitivity and Specificity of Procalcitonin in Diagnosing Bacterial Sepsis in Neonates

R Beaumont, K Tang, A Gwee - Hospital Pediatrics, 2024 - publications.aap.org
CONTEXT AND OBJECTIVES Neonatal sepsis accounts for 15% of all neonatal deaths.
Early detection enables prompt administration of antibiotic treatment, reducing morbidity and …

The differential expression of toll like receptors and RIG-1 in the placenta of neonates with in utero infections

M Rice, A Nicol, GJ Nuovo - Annals of Diagnostic Pathology, 2023 - Elsevier
Novel biomarkers of in utero infections are needed to help guide early therapy. The toll like
receptors (TLRs) and retinoic acid-inducible gene 1 (RIG-1) are proteins involved in the …

Long non‑coding RNAs MALAT1, NEAT1 and DSCR4 can be serum biomarkers in predicting urosepsis occurrence and reflect disease severity

J Shen, L Pan, W Chen, Y Wu - Experimental and …, 2024 - spandidos-publications.com
Sepsis commonly occurs in patients with serious infections. It severely threatens the health
of patients and has very high mortality rates. Urosepsis is a type of sepsis in which the …

Gut microbiome dysbiosis in neonatal sepsis

J Verma, MJ Sankar, K Atmakuri, R Agarwal… - Progress in Molecular …, 2022 - Elsevier
Sepsis is a highly heterogeneous, life-threatening organ dysfunction primarily caused by a
dysregulated immune response to counter bacterial, viral, or fungal infections, resulting in …

ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis

X Yang, L Lu, C Wu, F Zhang - Allergologia et Immunopathologia, 2023 - all-imm.com
Background: Sepsis is a life-threatening disease with dominant mortality. Its early diagnosis
and treatment can improve prognosis and reduce mortality. Long noncoding RNAs …

[HTML][HTML] 外周血单个核细胞Toll 样受体4 基因检测联合降钙素原对脓毒症的诊断价值研究

胡元慧, 汤冬玲, 张平安 - 中国全科医学, 2022 - chinagp.net
背景脓毒症是由感染引起的全身炎症反应综合征, 其发病率和致死率均较高,
早期诊断和治疗是防治脓毒症的关键, 但目前临床缺乏简便, 快速, 有效诊断脓毒症的检查指标 …

[HTML][HTML] Predictive Value of Toll-like Receptor 4 in Peripheral Blood Mononuclear Cells in Combination with Serum Procalcitonin for Sepsis

HU Yuanhui, T Dongling, Z Pingan - Chinese General Practice, 2022 - chinagp.net
Background Sepsis is an infection-caused systemic inflammatory response syndrome, with
relatively high morbidity and fatality rate. Early diagnosis and treatment are vital for …