[HTML][HTML] Focus: Organelles: Lipid droplets and the management of cellular stress

E Jarc, T Petan - The Yale journal of biology and medicine, 2019 - ncbi.nlm.nih.gov
Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of …

Lipid droplets and lipid mediators in viral infection and immunity

EA Monson, AM Trenerry, JL Laws… - FEMS microbiology …, 2021 - academic.oup.com
Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …

[HTML][HTML] Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death

M Danielli, L Perne, E Jarc Jovičić… - Frontiers in Cell and …, 2023 - frontiersin.org
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …

[HTML][HTML] A twist of FATe: Lipid droplets and inflammatory lipid mediators

E Jarc, T Petan - Biochimie, 2020 - Elsevier
Lipid droplets are fat storage organelles present in most eukaryotic cells. They consist of a
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …

[HTML][HTML] Symposium review: Mechanistic insights into adipose tissue inflammation and oxidative stress in periparturient dairy cows

M Zachut, GA Contreras - Journal of Dairy Science, 2022 - Elsevier
During the periparturient period, lipolysis in adipose tissue (AT) mobilizes fatty acid reserves
to meet high energy needs of dairy cows. This physiological response is accompanied by …

[HTML][HTML] Adipose tissue inflammation: linking physiological stressors to disease susceptibility

BJ Bradford, GA Contreras - Annual Review of Animal …, 2024 - annualreviews.org
The study of adipose tissue (AT) is enjoying a renaissance. White, brown, and beige
adipocytes are being investigated in adult animals, and the critical roles of small depots like …

[HTML][HTML] Perilipin 1 (Plin1) deficiency promotes inflammatory responses in lean adipose tissue through lipid dysregulation

JH Sohn, YK Lee, JS Han, YG Jeon, JI Kim… - Journal of Biological …, 2018 - ASBMB
Lipid droplets are specialized cellular organelles that contain neutral lipid metabolites and
play dynamic roles in energy homeostasis. Perilipin 1 (Plin1), one of the major lipid droplet …

[HTML][HTML] Lipid droplets control mitogenic lipid mediator production in human cancer cells

EJ Jovičić, AP Janež, TO Eichmann, Š Koren… - Molecular …, 2023 - Elsevier
Abstract Objectives Polyunsaturated fatty acids (PUFAs) are structural components of
membrane phospholipids and precursors of oxygenated lipid mediators with diverse …

[HTML][HTML] Friend or foe: lipid droplets as organelles for protein and lipid storage in cellular stress response, aging and disease

F Geltinger, L Schartel, M Wiederstein, J Tevini… - Molecules, 2020 - mdpi.com
Lipid droplets (LDs) were considered as a mere lipid storage organelle for a long time.
Recent evidence suggests that LDs are in fact distinct and dynamic organelles with a …

When fat meets the gut—focus on intestinal lipid handling in metabolic health and disease

M Wit, J Trujillo‐Viera, A Strohmeyer… - EMBO Molecular …, 2022 - embopress.org
The regular overconsumption of energy‐dense foods (rich in lipids and sugars) results in
elevated intestinal nutrient absorption and consequently excessive accumulation of lipids in …