Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …

Neurodegenerative diseases are severely debilitating conditions characterized primarily by
progressive neuronal loss and impairment of the nervous system. Alzheimer's and …

Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the
molecular and cellular processes involved in disorders of the nervous system. Adapting …

The accumulation of hyperphosphorylated tau protein aggregates is a key pathogenic event
in Alzheimer's disease (AD) and induces mitochondrial dysfunction and reactive oxygen …

Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive decline and irreversible memory impairment …

Crocin is a water-soluble carotenoid and has shown potential to improve the
neurodegenerative disease such as Alzheimer's disease (AD). However, its application is …

Human dental pulp stem cells (hDPSCs) have increasingly gained interest as a potential
therapy for nerve regeneration in medicine and dentistry, however their neurogenic potential …

A robust preclinical disease model is a primary requirement to understand the underlying
mechanisms, signaling pathways, and drug screening for human diseases. Although various …

Cell cultures are used in pharmaceutical, medical and biological sciences. Due to the ethical
and cost limitations of in vivo models, the replaceable cell model that is more closely related …

Modeling human neuronal properties in physiological and pathological conditions is
essential to identify novel potential drugs and to explore pathological mechanisms of …