Biological imaging of chemical bonds by stimulated Raman scattering microscopy

F Hu, L Shi, W Min - Nature methods, 2019 - nature.com
All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine

JX Cheng, XS Xie - Science, 2015 - science.org
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

High-speed molecular spectral imaging of tissue with stimulated Raman scattering

Y Ozeki, W Umemura, Y Otsuka, S Satoh… - Nature …, 2012 - nature.com
To date, medical imaging of tissues has largely relied on time-consuming staining
processes, and there is a need for rapid, label-free imaging techniques. Stimulated Raman …

[HTML][HTML] Computational coherent Raman scattering imaging: breaking physical barriers by fusion of advanced instrumentation and data science

H Lin, JX Cheng - eLight, 2023 - Springer
Coherent Raman scattering (CRS) microscopy is a chemical imaging modality that provides
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …

Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers

D Fu, G Holtom, C Freudiger, X Zhang… - The Journal of Physical …, 2013 - ACS Publications
Raman microscopy is a quantitative, label-free, and noninvasive optical imaging technique
for studying inhomogeneous systems. However, the feebleness of Raman scattering …

Coherent Raman scattering microscopy in biology and medicine

C Zhang, D Zhang, JX Cheng - Annual review of biomedical …, 2015 - annualreviews.org
Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …

Developments in spontaneous and coherent Raman scattering microscopic imaging for biomedical applications

C Krafft, IW Schie, T Meyer, M Schmitt… - Chemical Society …, 2016 - pubs.rsc.org
First, the potential role of Raman-based techniques in biomedicine is introduced. Second,
an overview about the instrumentation for spontaneous and coherent Raman scattering …

Broadband coherent Raman scattering microscopy

D Polli, V Kumar, CM Valensise… - Laser & Photonics …, 2018 - Wiley Online Library
Spontaneous Raman (SR) microscopy allows label‐free chemically specific imaging based
on the vibrational response of molecules; however, due to the low Raman scattering cross …

Review of stimulated Raman scattering microscopy techniques and applications in the biosciences

Y Li, B Shen, S Li, Y Zhao, J Qu, L Liu - Advanced Biology, 2021 - Wiley Online Library
Stimulated Raman scattering (SRS) microscopy is a nonlinear optical imaging method for
visualizing chemical content based on molecular vibrational bonds. Featuring high speed …

Soliton resonances and soliton molecules of pump wave and Stokes wave for a transient stimulated Raman scattering system in optics

BQ Li, YL Ma - The European Physical Journal Plus, 2022 - Springer
Pump wave and Stokes wave are two important pulse waves in modern nonlinear optics. In
this work, we study soliton resonance and soliton molecules of pump wave and Stokes wave …