Dendritic spines: the locus of structural and functional plasticity

C Sala, M Segal - Physiological reviews, 2014 - journals.physiology.org
The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

Exploring Single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs' Endothelial Corneal Dystrophy

GN Yang, YBY Sun, PK Roberts, H Moka… - Progress in Retinal and …, 2024 - Elsevier
Single-cell RNA sequencing (scRNA-seq) has enabled the identification of novel gene
signatures and cell heterogeneity in numerous tissues and diseases. Here we review the …

Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging

H Benaissa, K Ounoughi, I Aujard, E Fischer… - Nature …, 2021 - nature.com
Biocompatible fluorescent reporters with spectral properties spanning the entire visible
spectrum are indispensable tools for imaging the biochemistry of living cells and organisms …

Reduced microglial activity and enhanced glutamate transmission in the basolateral amygdala in early CNS autoimmunity

S Acharjee, M Verbeek, CD Gomez, K Bisht… - Journal of …, 2018 - Soc Neuroscience
Emotional dysfunction is common in multiple sclerosis (MS) patients and in mouse models of
MS, including experimental autoimmune encephalomyelitis (EAE); however, the etiology of …

Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease

CX Tang, J Chen, KQ Shao, YH Liu… - Neural Regeneration …, 2023 - journals.lww.com
Studies have found that the absence of glial cell line-derived neurotrophic factor may be the
primary risk factor for Parkinson's disease. However, there have not been any studies …

Modulation of behavior by scaffolding proteins of the post-synaptic density

C Gao, NC Tronson, J Radulovic - Neurobiology of learning and memory, 2013 - Elsevier
Scaffolding proteins of the neuronal post-synaptic density (PSD) are principal organizers of
glutamatergic neurotransmission that bring together glutamate receptors and signaling …

ADP-ribosylation factor 6 (ARF6) bidirectionally regulates dendritic spine formation depending on neuronal maturation and activity

Y Kim, SE Lee, J Park, M Kim, B Lee, D Hwang… - Journal of Biological …, 2015 - ASBMB
Recent studies have reported conflicting results regarding the role of ARF6 in dendritic spine
development, but no clear answer for the controversy has been suggested. We found that …

VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer

R Miao, X Guo, Q Zhi, Y Shi, L Li, X Mao, L Zhang… - PLoS One, 2013 - journals.plos.org
Vezatin (VEZT), an adherens junctions transmembrane protein, was identified as a putative
tumor suppressor in our previous study. However, the role of VEZT in tumorigenesis remains …

Impact of pharmacological and non-pharmacological modulators on dendritic spines structure and functions in brain

AM Mahalakshmi, B Ray, S Tuladhar, TA Hediyal… - Cells, 2021 - mdpi.com
Dendritic spines are small, thin, hair-like protrusions found on the dendritic processes of
neurons. They serve as independent compartments providing large amplitudes of Ca2+ …

Cellular junction dynamics and Alzheimer's disease: a comprehensive review

K Asghari, Z Niknam, S Mohammadpour-Asl… - Molecular Biology …, 2024 - Springer
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by
progressive neuronal damage and cognitive decline. Recent studies have shed light on the …