Toxoplasma gondii is an obligate intracellular protozoan parasite that causes opportunistic
disease, particularly in immunocompromised individuals. Central to its transmission and …

Toxoplasma gondii is one of the most successful protozoan parasites owing to its ability to
manipulate the immune system and establish a chronic infection. There are many T. gondii …

Toxoplasma gondii is a protozoan parasite of mammals and birds that is an important
human pathogen. Infection with this Apicomplexan parasite results in its dissemination …

The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host
cell that manipulate the immune response allowing it to establish a chronic infection …

Rapid discharge of secretory organelles called rhoptries is tightly coupled with host cell
entry by the protozoan parasite Toxoplasma gondii. Rhoptry contents were deposited in …

Toxoplasma is an obligate intracellular parasite that replicates in mammalian cells within a
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …

ABSTRACT Type II Toxoplasma gondii KU80 knockouts (Δ ku80) deficient in
nonhomologous end joining were developed to delete the dominant pathway mediating …

The intracellular parasite Toxoplasma gondii develops within a nonfusogenic vacuole
containing a network of elongated nanotubules that form connections with the vacuolar …

Strains of Toxoplasma gondii can be grouped into three predominant clonal lineages with
members of the type I group being uniformly lethal in mice. To elucidate the basis of this …

Genome-wide CRISPR screening is a powerful tool to identify genes required under
selective conditions. However, the inherent scale of genome-wide libraries can limit their …