PharmGKB, an integrated resource of pharmacogenomic knowledge

L Gong, M Whirl‐Carrillo, TE Klein - Current protocols, 2021 - Wiley Online Library
Abstract The Pharmacogenomics Knowledgebase (PharmGKB) is an integrated online
knowledge resource for the understanding of how genetic variation contributes to variation …

Assessment of clinically actionable pharmacogenetic markers to stratify anti-seizure medications

D Guin, Y Hasija, R Kukreti - The Pharmacogenomics Journal, 2023 - nature.com
Epilepsy treatment is challenging due to heterogeneous syndromes, different seizure types
and higher inter-individual variability. Identification of genetic variants predicting drug …

Text Mining Protocol to Retrieve Significant Drug–Gene Interactions from PubMed Abstracts

S Anand, OR Iyyappan, S Manoharan, D Anand… - Biomedical Text …, 2022 - Springer
Genes and proteins form the basis of all cellular processes and ensure a smooth functioning
of the human system. The diseases caused in humans can be either genetic in nature or …

Automated extraction of information from texts of scientific publications: insights Into HIV treatment strategies

N Biziukova, O Tarasova, S Ivanov, V Poroikov - Frontiers in genetics, 2020 - frontiersin.org
Text analysis can help to identify named entities (NEs) of small molecules, proteins, and
genes. Such data are very important for the analysis of molecular mechanisms of disease …

A novel text-mining approach for retrieving pharmacogenomics associations from the literature

MT Pandi, PJ Van der Spek, M Koromina… - Frontiers in …, 2020 - frontiersin.org
Text mining in biomedical literature is an emerging field which has already been shown to
have a variety of implementations in many research areas, including genetics, personalized …

[HTML][HTML] Advances in Clinical Pharmacogenomics and Prevention of Severe Cutaneous Adverse Drug Reactions in the Era of Precision Medicine

P Satapornpong, L Vorasatit, S John - 2024 - intechopen.com
Severe cutaneous adverse drug reactions (SCARs), including drug reactions with
eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic …

Identifying repurposed drugs with moderate anti-influenza virus activity through computational prioritization of drug-target pairs

B Taye, R Thuenauer, RJ Sugrue, S Maurer-Stroh… - bioRxiv, 2023 - biorxiv.org
Influenza A virus (IAV) causes up to five million cases of severe illness and half a million
deaths worldwide each year. While there are a few clinically approved drugs for treating IAV …

[图书][B] Knowledge-Driven Methods for Geographic Information Extraction in the Biomedical Domain

T Tahsin - 2019 - search.proquest.com
Accounting for over a third of all emerging and re-emerging infections, viruses represent a
major public health threat, which researchers and epidemiologists across the world have …