DNA microarrays enable researchers to monitor the expression of thousands of genes
simultaneously. However, the current technology has several limitations. Here we discuss …

Nucleic acid sequence variations have been implicated in many diseases, and reliable
detection and quantitation of DNA/RNA biomarkers can inform effective therapeutic action …

The relationships between the levels of transcripts and the levels of the proteins they encode
have not been examined comprehensively in mammals, although previous work in plants …

Although the existence of mammary stem cells has been suggested by serial transplantation
studies in mice, their identification has been hindered by the lack of specific surface markers …

Physical interactions between genetic elements located throughout the genome play
important roles in gene regulation and can be identified with the Chromosome Conformation …

The hair follicle bulge possesses putative epithelial stem cells. Characterization of these
cells has been hampered by the inability to target bulge cells genetically. Here, we use a …

Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal
antibody that targets the β-subunit of the pituitary hormone follicle-stimulating hormone (Fsh) …

The transcriptional profiles of mouse embryonic, neural, and hematopoietic stem cells were
compared to define a genetic program for stem cells. A total of 216 genes are enriched in all …

Bacterial communication via quorum sensing (QS) has been reported to be important in the
production of virulence factors, antibiotic sensitivity, and biofilm development. Two QS …

Background Several gene-expression signatures can be used to predict the prognosis in
diffuse large-B-cell lymphoma, but the lack of practical tests for a genome-scale analysis has …