Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

Extracellular vesicles (EVs) are nanoscale bilayer phospholipid membrane vesicles
released by cells. Contained large molecules such as nucleic acid, protein, and lipid, EVs …

Introduction The placenta is essential for fetal growth and survival and maintaining a
successful pregnancy. The sterility of the placenta has been challenged recently; however …

Objectives: To improve preclinical drug testing during pregnancy, we developed multiple
microfluidic organ-on-chip (OOC) devices that represent the structure, functions, and …

Cancer extracellular vesicles (EVs), or exosomes, promote tumor progression through
enhancing tumor growth, initiating epithelial-to-mesenchymal transition, remodeling the …

Small extracellular vesicles (sEVs), a subset of extracellular vesicles (EVs) originating from
the endosomal compartment, are a kind of lipid bilayer vesicles released by almost all types …

Extracellular vesicles (EVs) are double-layered lipid membrane vesicles released by cells.
Currently, EVs are attracting a lot of attention in the biological and medical fields due to their …

Background Fetal inflammatory response mediated by the influx of immune cells and
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …

During the last decade, organs-on-chips or organoids microphysiological analysis platforms
(MAP) have garnered attention in the practical applications of disease models, drug …

Genital mycoplasmas can break the cervical barrier and cause intraamniotic infection and
preterm birth. This study developed a six-chamber vagina-cervix-decidua-organ-on-a-chip …