Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Imaging mass spectrometry

LA McDonnell, RMA Heeren - Mass spectrometry reviews, 2007 - Wiley Online Library
Imaging mass spectrometry combines the chemical specificity and parallel detection of mass
spectrometry with microscopic imaging capabilities. The ability to simultaneously obtain …

[HTML][HTML] Mass spectrometry imaging with high resolution in mass and space

A Römpp, B Spengler - Histochemistry and cell biology, 2013 - Springer
Mass spectrometry (MS) imaging links molecular information and the spatial distribution of
analytes within a sample. In contrast to most histochemical techniques, mass spectrometry …

Mass spectrometry imaging for clinical research–latest developments, applications, and current limitations

PM Vaysse, RMA Heeren, T Porta, B Balluff - Analyst, 2017 - pubs.rsc.org
Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

DS Cornett, ML Reyzer, P Chaurand, RM Caprioli - Nature methods, 2007 - nature.com
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is
emerging as a powerful tool for investigating the distribution of molecules within biological …

MALDI imaging of lipid biochemistry in tissues by mass spectrometry

KA Zemski Berry, JA Hankin, RM Barkley… - Chemical …, 2011 - ACS Publications
As a result of recent advances, remarkable images revealing the distribution of complex
lipids in tissues are now generated by matrix-assisted laser desorption/ionization imaging …

A concise review of mass spectrometry imaging

ERA van Hove, DF Smith, RMA Heeren - Journal of chromatography A, 2010 - Elsevier
Mass spectrometric imaging allows the investigation of the spatial distribution of molecules
at complex surfaces. The combination of molecular speciation with local analysis renders a …

MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery

MM Gessel, JL Norris, RM Caprioli - Journal of proteomics, 2014 - Elsevier
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS)
combines the sensitivity and selectivity of mass spectrometry with spatial analysis to provide …

Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences

RJA Goodwin - Journal of proteomics, 2012 - Elsevier
Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface
of a wide variety of samples, allowing the multiplex measurement of both abundance and …

Ultra-high mass resolving power, mass accuracy, and dynamic range MALDI mass spectrometry imaging by 21-T FT-ICR MS

AP Bowman, GT Blakney, CL Hendrickson… - Analytical …, 2020 - ACS Publications
Detailed characterization of complex biological surfaces by matrix-assisted laser
desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation …