Synthetic chlorins, possible surrogates for chlorophylls, prepared by derivatization of porphyrins

M Taniguchi, JS Lindsey - Chemical reviews, 2017 - ACS Publications
Chlorophylls make Earth green, are the central constituents in the engine of photosynthesis,
and not surprisingly have garnered immense attention. A chlorin, the core chromophore of a …

The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade

A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Current state of the nanoscale delivery systems for temoporfin-based photodynamic therapy: Advanced delivery strategies

I Yakavets, M Millard, V Zorin, HP Lassalle… - Journal of Controlled …, 2019 - Elsevier
Enthusiasm for photodynamic therapy (PDT) as a promising technique to eradicate various
cancers has increased exponentially in recent decades. The majority of clinically approved …

[HTML][HTML] Photodynamic therapy for inflammatory and cancerous diseases of the intestines: molecular mechanisms and prospects for application

B Deng, K Wang, L Zhang, Z Qiu, W Dong… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a minimally invasive treatment that effectively targets cancer
and inflammatory diseases. It has gained recognition for its efficacy, low toxicity, and …

Hydrogels: soft matters in photomedicine

B Khurana, P Gierlich, A Meindl… - Photochemical & …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT), a shining beacon in the realm of photomedicine, is a non-
invasive technique that utilizes dye-based photosensitizers (PSs) in conjunction with light …

Regioselective and stepwise syntheses of functionalized BODIPY dyes through palladium-catalyzed cross-coupling reactions and direct C–H arylations

Z Feng, L Jiao, Y Feng, C Yu, N Chen… - The Journal of …, 2016 - ACS Publications
Regioselective and stepwise syntheses of a series of functionalized BODIPY dyes through
palladium-catalyzed cross-coupling reactions and direct C–H arylations have been …

DNA targeting long-chain alkoxy appended tin (IV) porphyrin scaffolds: photophysical and antimicrobial PDT investigations

M Ravikumar, D Raghav, K Rathinasamy… - ACS Applied Bio …, 2018 - ACS Publications
Tin (IV) porphyrin scaffolds having long-chain (C8 and C16) alkoxyphenyl group at one
meso position were synthesized with axial dichloro and dihydroxo ligands. Modifications …

[HTML][HTML] Photodynamic therapy with HiPorfin for cervical squamous intraepithelial lesion at childbearing age

Y Liu, R Wu, C Li, L Wei, R Li - Photodiagnosis and Photodynamic Therapy, 2024 - Elsevier
Objective To evaluate the clinical efficacy and safety of HiPorfin® photodynamic therapy
(PDT) in the treatment of young women at reproductive age with high-grade squamous …

One‐Photon and Two‐Photon Photophysical Properties of Tetrafunctionalized 5,10,15,20‐tetrakis(m‐hydroxyphenyl)chlorin (Temoporfin) Derivatives as Potential …

P Gierlich, SG Mucha, E Robbins… - …, 2022 - Wiley Online Library
Photodynamic therapy (PDT) is a cancer treatment, which exploits a photosensitizing drug
and light to produce reactive oxygen species that can cause selective damage to the target …

Soret band shape indicates mTHPC distribution between β-cyclodextrins and serum proteins

I Yakavets, I Yankovsky, L Bezdetnaya, V Zorin - Dyes and Pigments, 2017 - Elsevier
Fluorescence and absorbance characteristics of 5, 10, 15, 20-tetra (m-hydroxyphenyl)
chlorin (mTHPC) in several organic solutions and in complexes with various biological …