Biological studies of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …
considered to be known: that is, an event that involves threat to the physical integrity of …
Single-prolonged stress: a review of two decades of progress in a rodent model of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric
condition. However, the biological mechanisms underlying this disease are still largely …
condition. However, the biological mechanisms underlying this disease are still largely …
The traumatic stress response in child maltreatment and resultant neuropsychological effects
Child maltreatment is a pervasive problem in our society that has long-term detrimental
consequences to the development of the affected child such as future brain growth and …
consequences to the development of the affected child such as future brain growth and …
Animal models of PTSD: a critical review
EI Flandreau, M Toth - Behavioral Neurobiology of PTSD, 2018 - Springer
The goals of animal research in post-traumatic stress disorder (PTSD) include better
understanding the neurophysiological etiology of PTSD, identifying potential targets for …
understanding the neurophysiological etiology of PTSD, identifying potential targets for …
Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine
Apart from altered dopamine (DA) function, schizophrenia displays mitochondrial and
immune-inflammatory abnormalities, evidenced by oxidative stress, altered kynurenine …
immune-inflammatory abnormalities, evidenced by oxidative stress, altered kynurenine …
Sampling blood from the lateral tail vein of the rat
G Lee, KA Goosens - Journal of visualized experiments: JoVE, 2015 - pmc.ncbi.nlm.nih.gov
Blood samples are commonly obtained in many experimental contexts to measure targets of
interest, including hormones, immune factors, growth factors, proteins, and glucose, yet the …
interest, including hormones, immune factors, growth factors, proteins, and glucose, yet the …
Alterations in monoamine levels and oxidative systems in frontal cortex, striatum, and hippocampus of the rat brain during chronic unpredictable stress
Stress plays a key role in the induction of various clinical disorders by altering
monoaminergic response and antioxidant defenses. In the present study, alterations in the …
monoaminergic response and antioxidant defenses. In the present study, alterations in the …
Modelling posttraumatic stress disorders in animals
Animal models of posttraumatic stress disorder are useful tools to reveal the neurobiological
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …
Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression
The neurochemical basis of depression focuses on alterations in the monoaminergic and
amino acid neurotransmitter systems. Moreover, decreases in serum levels of the …
amino acid neurotransmitter systems. Moreover, decreases in serum levels of the …
Social stress during adolescence in Wistar rats induces social anxiety in adulthood without affecting brain monoaminergic content and activity
Adolescence has been described as an important period to acquire social competences
required for adult life. It has been suggested that early stress experiences could affect the …
required for adult life. It has been suggested that early stress experiences could affect the …