In multicellular organisms, cellular behaviour is tightly regulated to allow proper embryonic
development and maintenance of adult tissue. A critical component in this control is the …

To build a complex body composed of various cell types and tissues and to maintain tissue
homeostasis in the postembryonic period, animals use a small number of highly conserved …

The fucosylation of glycoproteins regulates diverse physiological processes. Inhibitors that
can control cellular levels of protein fucosylation have consequently emerged as being of …

Notch signaling is a cellular pathway regulating cell-fate determination and adult tissue
homeostasis. Little is known about how canonical Notch ligands or Fringe enzymes …

Notch signaling, which was initially identified in Drosophila wing morphogenesis, plays
pivotal roles in cell development and differentiation. Optimal Notch pathway activity is …

The 100th anniversary of Notch discovery in Drosophila has recently passed. The Notch is
evolutionarily conserved from Drosophila to humans. The discovery of human-specific Notch …

NOTCH1 is a transmembrane receptor that initiates a cell–cell signaling pathway controlling
various cell fate specifications in metazoans. The addition of O-fucose by protein O …

Notch signaling plays various roles in cell-fate specification through direct cell–cell
interactions. Notch receptors are evolutionarily conserved transmembrane proteins with …

Bacillus thuringiensis (Bt) proteins are an environmentally safe and effective alternative to
chemical pesticides and have been used as biopesticides, with great commercial success …

The Drosophila tracheal system is a favorable model for investigating the program of tubular
morphogenesis. This system is established in the embryo by post-mitotic cells, but also …