Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …

Iron is a micronutrient essential for cellular energy and metabolism, necessary for
maintaining body homoeostasis. Iron deficiency is an important co-morbidity in patients with …

Neutrophil gelatinase-associated lipocalin (NGAL) is a small circulating protein that is highly
modulated in a wide variety of pathological situations, making it a useful biomarker of …

The high incidence of cardiomyopathy in patients with hemosiderosis, particularly in
transfusional iron overload, strongly indicates that iron accumulation in the heart plays a …

The interest in the role of ferrous iron in diabetes pathophysiology has been revived by
recent evidence of iron as an important determinant of pancreatic islet inflammation and as a …

Biological and chemical agents cause dangerous effects on human health via different
exposing ways. Recently, herbal medicine is considered as a biological and safe treatment …

Our objective was to determine whether lipocalin-2 (Lcn2) regulates cardiomyocyte
apoptosis, the mechanisms involved, and the functional significance. Emerging evidence …

In the present study, we demonstrate the coaction of thioredoxin and glutathione (GSH)
systems in mouse liver against iron overload‐induced oxidative stress (OS). Mice were …

Cardiac disorders remain one of the most important causes of death in the world. Oxidative
stress has been suggested as one of the molecular mechanisms involved in drug-induced …

BACKGROUND & AIMS: Most data on the effects of iron chelation therapy for patients with
liver fibrosis come from small studies. We studied the effects of the oral iron chelator …