Ultra-processed diet, systemic oxidative stress, and breach of immunologic tolerance

EEM Leo, AM Peñafiel, VMH Escalante, ZMC Araujo - Nutrition, 2021 - Elsevier
In recent years, consumption of ultra-processed food around the world has been increasing.
The nutritional profile of an ultra-processed diet is associated with the development of …

The role of nitric oxide in stem cell biology

E Caballano-Infantes, GM Cahuana, FJ Bedoya… - Antioxidants, 2022 - mdpi.com
Nitric oxide (NO) is a gaseous biomolecule endogenously synthesized with an essential role
in embryonic development and several physiological functions, such as regulating …

[HTML][HTML] Epigenetic Regulation of Angiogenesis in Peripheral Artery Disease

NK Malhi, KW Southerland, L Lai… - Methodist DeBakey …, 2023 - ncbi.nlm.nih.gov
Peripheral arterial disease (PAD) represents a global health concern with a rising
prevalence attributed to factors such as obesity, diabetes, aging, and smoking. Among …

Transflammation in tissue regeneration and response to injury: How cell-autonomous inflammatory signaling mediates cell plasticity

JP Cooke, L Lai - Advanced Drug Delivery Reviews, 2023 - Elsevier
Inflammation is a first responder against injury and infection and is also critical for the
regeneration and repair of tissue after injury. The role of professional immune cells in tissue …

CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID

D Thomas, C Noishiki, S Gaddam, D Wu… - Nature Cardiovascular …, 2024 - nature.com
Evidence linking the endothelium to cardiac injury in long coronavirus disease (COVID) is
well documented, but the underlying mechanisms remain unknown. Here we show that …

Consecutive hypoxia decreases expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 downregulation and intermittent hypoxia-reoxygenation increases …

YY Yang, CJ Lin, CC Wang, CM Chen… - Frontiers in Cell and …, 2020 - frontiersin.org
Previous studies have shown that the experimental models of hypoxia-reoxygenation (H/R)
mimics the physiological conditions of ischemia-reperfusion and induce oxidative stress and …

Stemness of human pluripotent cells: Hypoxia-like response induced by low nitric oxide

E Caballano-Infantes, I Díaz, AB Hitos, GM Cahuana… - Antioxidants, 2021 - mdpi.com
The optimization of conditions to promote the stemness of pluripotent cells in vitro is
instrumental for their use in advanced therapies. We show here that exposure of human …

[图书][B] Generation of human ipscs by protein reprogramming and stimulation of Tlr3 signaling

C Liu, M Ameen, S Himmati, D Thomas, N Sayed - 2021 - Springer
The discovery of induced pluripotent stem cells (iPSCs) allows for establishment of human
embryonic stem-like cells from various adult human somatic cells (eg, fibroblasts), without …

Immunostimulant bathing influences the expression of immune-and metabolic-related genes in Atlantic Salmon alevins

F Figueiredo, H Kristoffersen, S Bhat, Z Zhang… - Biology, 2021 - mdpi.com
Simple Summary Activation of immune cells is bioenergetically expensive, requiring precise
control of cellular metabolism. This applies also to innate immune cells. The current study …

Efectos de la lecitina de soya en parámetros hematológicos y marcadores inflamatorios sistémicos de ratas

L Cala Calviño, H Cruz Vadell… - Revista Cubana de …, 2024 - scielo.sld.cu
Introducción: El estudio de los efectos farmacológicos preclínicos de la lecitina de soya
sobre parámetros hematológicos y marcadores inflamatorios sistémicos, contribuirá a …