Strategies for chiral separation: from racemate to enantiomer

J Sui, N Wang, J Wang, X Huang, T Wang, L Zhou… - Chemical …, 2023 - pubs.rsc.org
Chiral separation has already become a crucial topic for effectively utilizing superfluous
racemates synthesized by chemical means and satisfying the growing requirements for …

Chiral polymeric membranes: Recent applications and trends

P Vedovello, CM Paranhos, C Fernandes… - Separation and …, 2022 - Elsevier
The development and marked growth of chiral compounds is primarily due to the increased
demand for pharmaceutical applications, but it has been also extended to other sectors like …

Trifunctional strategy for the design and synthesis of a Ni-CeO2@ SiO2 catalyst with remarkable low-temperature sintering and coking resistance for methane dry …

S Lin, J Wang, Y Mi, S Yang, Z Wang, W Liu… - Chinese Journal of …, 2021 - Elsevier
In this study, a trifunctional strategy was developed to prepare a confined Ni-based catalyst
(Ni-CeO 2@ SiO 2) for dry reforming of methane (DRM) of two main greenhouse gases—CO …

State of the Art in Crystallization‐Induced Diastereomer Transformations

A Kolarovič, P Jakubec - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Crystallization‐induced diastereomer transformations (CIDT) enable isolation of the target
compounds in high enantio‐and diastereomeric purities and with up to quantitative yields …

Simultaneous chiral resolution of two racemic compounds by preferential cocrystallization

F Zhou, O Shemchuk, MD Charpentier… - Angewandte …, 2021 - Wiley Online Library
We tap into an unexplored area of preferential crystallization, being the first to develop
simultaneous chiral resolution of two racemic compounds by preferential cocrystallization …

Case of chiral resolution through converting two racemic compounds into a conglomerate

L Wang, N Wang, J Sui, S Sun, Z Feng, G Li… - Crystal Growth & …, 2023 - ACS Publications
The formation of a conglomerate is always attractive, which is a prerequisite for chiral
resolution by a flexible and productive preferential crystallization. This present study is …

Comparing and quantifying the efficiency of cocrystal screening methods for Praziquantel

MD Charpentier, JJ Devogelaer, A Tijink… - Crystal Growth & …, 2022 - ACS Publications
Pharmaceutical cocrystals are highly interesting due to their effect on physicochemical
properties and their role in separation technologies, particularly for chiral molecules …

Mechanochemical synthesis of cocrystal: From mechanism to application

Y Xiao, C Wu, X Hu, K Chen, L Qi, P Cui… - Crystal Growth & …, 2023 - ACS Publications
Cocrystal engineering is gaining interest across various disciplines since it can effectively
tune the properties of solid substances via noncovalent synthesis by introducing new …

Deracemization of Atropisomeric Biaryls Enabled by Copper Catalysis

J Zhang, K Wang, C Zhu - JACS Au, 2024 - ACS Publications
Atropisomeric biaryls have found crucial applications in versatile chiral catalysts as well as
in ligands for transition metals. Herein, we have developed an efficient crystallization …

Chiral resolution of mandelic acid through preferential cocrystallization with nefiracetam

X Buol, C Caro Garrido, K Robeyns… - Crystal Growth & …, 2020 - ACS Publications
In this paper, we identified a cocrystal conglomerate of mandelic acid using a drug
compound as a coformer. We then developed a chiral resolution process based on …