Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …
responsible for causing life-threatening infections. The emergence of hypervirulent and …
Subtractive genomics profiling for potential drug targets identification against Moraxella catarrhalis
Moraxella catarrhalis (M. catarrhalis) is a gram-negative bacterium, responsible for major
respiratory tract and middle ear infection in infants and adults. The recent emergence of the …
respiratory tract and middle ear infection in infants and adults. The recent emergence of the …
Determine the potential epitope based peptide vaccine against novel SARS-CoV-2 targeting structural proteins using immunoinformatics approaches
Coronaviruses (CoVs) belong to the Coronaviridae-family. The genus Beta-coronaviruses,
are enveloped positive strand RNA viruses with club-like spikes at the surface with a unique …
are enveloped positive strand RNA viruses with club-like spikes at the surface with a unique …
Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope‐Based Peptide Vaccine and Novel Compounds against Novel SARS‐CoV‐2 …
Background. Coronaviruses (CoVs) are enveloped positive‐strand RNA viruses which have
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs against them: An in silico approach
Monkeypox virus (mpox virus) outbreak has rapidly spread to 82 non-endemic countries.
Although it primarily causes skin lesions, secondary complications and high mortality (1 …
Although it primarily causes skin lesions, secondary complications and high mortality (1 …
Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis
JA Hammond, EA Gordon, KM Socarras… - Biochemical Society …, 2020 - portlandpress.com
The principle of monoclonality with regard to bacterial infections was considered immutable
prior to 30 years ago. This view, espoused by Koch for acute infections, has proven …
prior to 30 years ago. This view, espoused by Koch for acute infections, has proven …
Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics …
S Marriam, MS Afghan, M Nadeem, M Sajid… - Frontiers in Cellular …, 2023 - frontiersin.org
There has been progressive improvement in immunoinformatics approaches for epitope-
based peptide design. Computational-based immune-informatics approaches were applied …
based peptide design. Computational-based immune-informatics approaches were applied …
Comparative Genomics of Histoplasma capsulatum and Prediction of New Vaccines and Drug Targets
PCS Almeida, BS Roque, AG Felice, AK Jaiswal… - Journal of Fungi, 2023 - mdpi.com
Histoplasma capsulatum is a thermodymorphic fungus that causes histoplasmosis, a
systemic mycosis that presents different clinical manifestations, ranging from self-limiting to …
systemic mycosis that presents different clinical manifestations, ranging from self-limiting to …
Rational design of multimeric based subunit vaccine against Mycoplasma pneumonia: Subtractive proteomics with immunoinformatics framework
Mycoplasma pneumoniae is the prevalent cause of acquired respiratory infections around
the globe. A multi-epitope vaccine (MEV) must be developed to combat infections of M …
the globe. A multi-epitope vaccine (MEV) must be developed to combat infections of M …