Hydrogen sulfide: from a toxic molecule to a key molecule of cell life

A Aroca, C Gotor, DC Bassham, LC Romero - Antioxidants, 2020 - mdpi.com
Hydrogen sulfide (H2S) has always been considered toxic, but a huge number of articles
published more recently showed the beneficial biochemical properties of its endogenous …

Supersulfide biology and translational medicine for disease control

U Barayeu, T Sawa, M Nishida, FY Wei… - British Journal of …, 2023 - Wiley Online Library
For decades, the major focus of redox biology has been oxygen, the most abundant element
on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial …

A photo‐responsive hollow manganese/carbon hybrid nanosphere for wound disinfection and healing

M Lu, S Li, X Xiong, Z Huang, B Xu… - Advanced Functional …, 2022 - Wiley Online Library
The emergence of multi‐drug resistant (MDR) bacteria poses a serious threat to human
health. It has become imperative to develop efficient antimicrobial strategies. Here, a …

Direct proteomic mapping of cysteine persulfidation

L Fu, K Liu, J He, C Tian, X Yu, J Yang - Antioxidants & redox …, 2020 - liebertpub.com
Aims: Cysteine persulfidation (also called sulfhydration or sulfuration) has emerged as a
potential redox mechanism to regulate protein functions and diverse biological processes in …

Sensing and regulation of reactive sulfur species (RSS) in bacteria

DP Giedroc, GT Antelo, JN Fakhoury… - Current Opinion in …, 2023 - Elsevier
The infected host deploys generalized oxidative stress caused by small inorganic reactive
molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H 2 …

Cysteine and resistance to oxidative stress: implications for virulence and antibiotic resistance

A Tikhomirova, MM Rahman, SP Kidd, RL Fererro… - Trends in …, 2024 - cell.com
Reactive oxygen species (ROS), including the superoxide radical anion (O 2•–), hydrogen
peroxide (H 2 O 2), and the hydroxyl radical (• HO), are inherent components of bacterial …

Chemical biology of reactive sulfur species: hydrolysis-driven equilibrium of polysulfides as a determinant of physiological functions

T Sawa, T Takata, T Matsunaga, H Ihara… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Polysulfide species (ie, RS nR′, n> 2; and RS nH, n> 1) exist in many
organisms. The highly nucleophilic nature of hydropersulfides and hydropolysulfides …

Hydrogen sulfide in physiology and pathogenesis of bacteria and viruses

VK Pal, P Bandyopadhyay, A Singh - IUBMB life, 2018 - Wiley Online Library
An increasing number of studies have established hydrogen sulfide (H2S) gas as a major
cytoprotectant and redox modulator. Following its discovery, H2S has been found to have …

Label-Free Quantitative Proteomic Analysis of Nitrogen Starvation in Arabidopsis Root Reveals New Aspects of H2S Signaling by Protein Persulfidation

A Jurado-Flores, LC Romero, C Gotor - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S)-mediated signaling pathways regulate many physiological and
pathophysiological processes in mammalian and plant systems. The molecular mechanism …

[HTML][HTML] Redox regulation by reversible protein S-thiolation in Gram-positive bacteria

M Imber, AJ Pietrzyk-Brzezinska, H Antelmann - Redox biology, 2019 - Elsevier
Low molecular weight (LMW) thiols play an important role as thiol-cofactors for many
enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative …